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Age and sex-adjusted incidence and yearly prevalence of multiple sclerosis (MS) in Mazandaran province, Iran: An 11-years study

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  • Hamed Cheraghmakani
  • Seyed Mohammad Baghbanian
  • Reza HabibiSaravi
  • Arash Azar
  • Fariba Ghasemihamedani

Abstract

Introduction: The incidence rate of MS is a valuable indicator of the recent changes in the risk of this disease, and it is widely implicated for health planning purposes. Objectives: This study aims to determine the MS incidence over the past eleven years in Mazandaran province and to compare it with the other parts of Iran and the world. Materials and methods: This retrospective study is conducted in Mazandaran province by using registered data in the files of the patients with their consent. The yearly crude incidence rates, age, and sex-specific incidence rates and directly standardized incidence rates of this population are calculated, and the temporal changes in the incidence rates are analyzed. Results: 662 (26%) male patients with the mean (SD) age of 32.6 (9.48) and 1884 (74%) female patients with the mean (SD) age of 31.9 (9.15) are studied. The direct standardized incidence rate of MS was 3.28 in 100.000 in 2008 and reached 4.17 in 100.000 in 2018, and this increase was significant (p

Suggested Citation

  • Hamed Cheraghmakani & Seyed Mohammad Baghbanian & Reza HabibiSaravi & Arash Azar & Fariba Ghasemihamedani, 2020. "Age and sex-adjusted incidence and yearly prevalence of multiple sclerosis (MS) in Mazandaran province, Iran: An 11-years study," PLOS ONE, Public Library of Science, vol. 15(7), pages 1-11, July.
    • Handle: RePEc:plo:pone00:0235562
    DOI: 10.1371/journal.pone.0235562
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    1. Cecilia Ahlgren & Anders Odén & Jan Lycke, 2014. "High Nationwide Incidence of Multiple Sclerosis in Sweden," PLOS ONE, Public Library of Science, vol. 9(9), pages 1-6, September.
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