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Long-term effects on growth of an energy-enhanced parenteral nutrition in preterm newborn: A quasi-experimental study

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Listed:
  • Gianluca Terrin
  • Alessandra Coscia
  • Giovanni Boscarino
  • Francesca Faccioli
  • Maria Di Chiara
  • Carla Greco
  • Elisa Onestà
  • Salvatore Oliva
  • Marina Aloi
  • Lucia Dito
  • Viviana Cardilli
  • Daniela Regoli
  • Mario De Curtis

Abstract

Aim: To assess the best energy intake in Parenteral Nutrition (PN) for preterm newborns, considering both possible benefits for growth and risk of complications. Methods: Quasi-experimental study comparing two cohorts of newborns, receiving Energy-Enhanced vs. Standard PN (Cohort A, from 1st January 2015 to 31 January 2016 and Cohort B from 1st February 2016 to 31 March 2017; respectively) after implementation of a change in the PN protocol. The primary outcome measure was growth at 24 months of life. The PN associated complications were also measured. Results: We enrolled 132 newborns in two Cohorts, similar for prenatal and postnatal clinical characteristics. Although, body weight and length at 24 months of life were significantly higher (p

Suggested Citation

  • Gianluca Terrin & Alessandra Coscia & Giovanni Boscarino & Francesca Faccioli & Maria Di Chiara & Carla Greco & Elisa Onestà & Salvatore Oliva & Marina Aloi & Lucia Dito & Viviana Cardilli & Daniela R, 2020. "Long-term effects on growth of an energy-enhanced parenteral nutrition in preterm newborn: A quasi-experimental study," PLOS ONE, Public Library of Science, vol. 15(7), pages 1-15, July.
    • Handle: RePEc:plo:pone00:0235540
    DOI: 10.1371/journal.pone.0235540
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