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Proposal of the optimal numbers of examined and positive lymph nodes to the 8th edition of American Joint Committee on Cancer (AJCC) staging for 758 patients with distal cholangiocarcinoma

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  • RuiYang Wu
  • Gang Zhang
  • Jiao Feng
  • Liang Zhang
  • ZhiMing Yang

Abstract

Introduction: The American Joint Committee on Cancer (AJCC) recommended retrieval of at least 12 lymph nodes and firstly classified N category by the number of positive lymph nodes (PLNs) for Distal Cholangiocarcinoma (DCC). Objective: The end of this cohort study was to explore the optimal cut-off values of the number of examined lymph nodes (ELNs) and PLNs to better stratify patients by utilizing a population-based database. Methods: A number of 758 patients with DCC from the Surveillance, Epidemiology, and End Results (SEER) database were enrolled in the study and comparing by the survival analysis. Results: Survival analysis found that patients with ELNs

Suggested Citation

  • RuiYang Wu & Gang Zhang & Jiao Feng & Liang Zhang & ZhiMing Yang, 2020. "Proposal of the optimal numbers of examined and positive lymph nodes to the 8th edition of American Joint Committee on Cancer (AJCC) staging for 758 patients with distal cholangiocarcinoma," PLOS ONE, Public Library of Science, vol. 15(6), pages 1-10, June.
    • Handle: RePEc:plo:pone00:0234464
    DOI: 10.1371/journal.pone.0234464
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