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Risks of tinnitus, sensorineural hearing impairment, and sudden deafness in patients with non-migraine headache

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  • Yi-Chun Chen
  • Shiang-Jiun Tsai
  • Jin-Cherng Chen
  • Juen-Haur Hwang

Abstract

Tinnitus and hearing impairment are prevalent among headache patients. This study aims to investigate the risk of tinnitus, sensorineural hearing impairment, and sudden deafness in patients with non-migraine headache. Participants included 43 294 patients with non-migraine headache (non-migraine headache cohort) and 173 176 patients with no headache of any type (control cohort) frequency-matched with respect to 10-year age interval and sex from the Longitudinal Health Insurance Database 2005 of the Taiwan National Health Insurance Research Database. The mean age of the non-migraine headache cohort was 28.4 ± 14.9 years, and 58.5% of this cohort was male. The incidence rates of tinnitus, sensorineural hearing impairment, and sudden deafness were compared between cohorts using the Kaplan–Meier method with the log-rank test. A Cox proportional hazard model was used to examine the association of tinnitus, sensorineural hearing impairment, and sudden deafness with non-migraine headache, with adjustment for all covariates. The combined risk of either tinnitus, sensorineural hearing impairment, or sudden deafness was higher in the non-migraine headache cohort than in the control cohort (adjusted odds ratio [aHR], 2.73; 95% confidence interval [95% CI], 2.62–2.84; p

Suggested Citation

  • Yi-Chun Chen & Shiang-Jiun Tsai & Jin-Cherng Chen & Juen-Haur Hwang, 2019. "Risks of tinnitus, sensorineural hearing impairment, and sudden deafness in patients with non-migraine headache," PLOS ONE, Public Library of Science, vol. 14(9), pages 1-10, September.
    • Handle: RePEc:plo:pone00:0222041
    DOI: 10.1371/journal.pone.0222041
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