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Higher medical costs for CKD patients with a rapid decline in eGFR: A cohort study from the Japanese general population

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  • Kei Nagai
  • Chiho Iseki
  • Kunitoshi Iseki
  • Masahide Kondo
  • Koichi Asahi
  • Chie Saito
  • Ryoya Tsunoda
  • Reiko Okubo
  • Kunihiro Yamagata

Abstract

To investigate how changes in eGFR can affect medical costs, a regional cohort of national health insurance beneficiaries in Japan was developed from a nationwide database system (Kokuho database, KDB), and non-individualized data were obtained. From 105,661 people, subjects on chronic dialysis and subjects without consecutive medical checkups were excluded. Finally, medical costs in the follow-up year categorized by annual changes in eGFR between baseline and the next year were longitudinally examined in 70,627 people ranging in age from 40 to 74 years. Global mean costs for subjects with a rapid decrease in eGFR (≤-30%/year) were the highest among all ΔeGFR categories. In men, the cost was 1.42 times that for a stable eGFR. A total of 6,268 (19.4%) men and 5,381 (14.0%) women with eGFR

Suggested Citation

  • Kei Nagai & Chiho Iseki & Kunitoshi Iseki & Masahide Kondo & Koichi Asahi & Chie Saito & Ryoya Tsunoda & Reiko Okubo & Kunihiro Yamagata, 2019. "Higher medical costs for CKD patients with a rapid decline in eGFR: A cohort study from the Japanese general population," PLOS ONE, Public Library of Science, vol. 14(5), pages 1-11, May.
    • Handle: RePEc:plo:pone00:0216432
    DOI: 10.1371/journal.pone.0216432
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