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The association of CHA2DS2-VASc score and carotid plaque in patients with non-valvular atrial fibrillation

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  • Luxiang Shang
  • Yang Zhao
  • Mengjiao Shao
  • Huaxin Sun
  • Min Feng
  • Yaodong Li
  • Xianhui Zhou
  • Baopeng Tang

Abstract

Objective: The aim of this study was to assess the association between CHA2DS2-VASc score and carotid plaques in patients with non-valvular atrial fibrillation (NVAF). Methods: We conducted a retrospective study including 3,435 NVAF patients who underwent carotid ultrasound examinations from January 2015 to December 2017.We collected the clinical data on the medical records system. Chi-square trend test was used to analyze trends between the prevalence of carotid plaques with an increasing CHA2DS2-VASc score. Univariate and multivariate logistic regression was also used to assess the association between carotid plaques and CHA2DS2-VASc scores. The area under the receiver operating characteristic (ROC) curve (AUC) was used to determine the optimal cutoff points of different CHA2DS2-VASc scores in NVAF patients. Results: NVAF patients with carotid plaques had higher CHA2DS2-VASc scores compared with patients who did not have carotid plaques (3.01±1.36 vs. 2.55±1.28, P

Suggested Citation

  • Luxiang Shang & Yang Zhao & Mengjiao Shao & Huaxin Sun & Min Feng & Yaodong Li & Xianhui Zhou & Baopeng Tang, 2019. "The association of CHA2DS2-VASc score and carotid plaque in patients with non-valvular atrial fibrillation," PLOS ONE, Public Library of Science, vol. 14(2), pages 1-9, February.
    • Handle: RePEc:plo:pone00:0210945
    DOI: 10.1371/journal.pone.0210945
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