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Predialysis anemia management and outcomes following dialysis initiation: A retrospective cohort analysis

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  • James B Wetmore
  • Suying Li
  • Heng Yan
  • Hairong Xu
  • Yi Peng
  • Marvin V Sinsakul
  • Jiannong Liu
  • David T Gilbertson

Abstract

Whether and how anemia treatment with erythropoiesis stimulating agents (ESAs) before hemodialysis initiation may be associated with lower mortality after dialysis initiation is unknown. We compared all-cause and cardiovascular mortality in two groups of patients who experienced distinct anemia treatment patterns with ESAs before and after hemodialysis initiation. This retrospective cohort analysis included patients initiating hemodialysis April 1, 2012-June 30, 2013, identified from United States Renal Data System end-stage renal disease (ESRD) and pre-ESRD files. Patients treated with ESAs before and after hemodialysis initiation who maintained Hb ≥ 9.0 g/dL throughout (comparator group, n = 3662) were compared with patients with Hb

Suggested Citation

  • James B Wetmore & Suying Li & Heng Yan & Hairong Xu & Yi Peng & Marvin V Sinsakul & Jiannong Liu & David T Gilbertson, 2018. "Predialysis anemia management and outcomes following dialysis initiation: A retrospective cohort analysis," PLOS ONE, Public Library of Science, vol. 13(9), pages 1-14, September.
    • Handle: RePEc:plo:pone00:0203767
    DOI: 10.1371/journal.pone.0203767
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    Cited by:

    1. Selma Alagoz & Mevlut Tamer Dincer & Necmi Eren & Alev Bakir & Meltem Pekpak & Sinan Trabulus & Nurhan Seyahi, 2020. "Prevalence of anemia in predialysis chronic kidney disease: Is the study center a significant factor?," PLOS ONE, Public Library of Science, vol. 15(4), pages 1-9, April.

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