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SYNTAX score II predicts long-term mortality in patients with one- or two-vessel disease

Author

Listed:
  • Maxime M Vroegindewey
  • Anne-Sophie Schuurman
  • Rohit M Oemrawsingh
  • Robert-Jan van Geuns
  • Isabella Kardys
  • Jurgen Ligthart
  • Joost Daemen
  • Eric Boersma
  • Patrick W Serruys
  • K Martijn Akkerhuis

Abstract

Objective: SYNTAX score II (SSII) is a long-term mortality prediction model to guide the decision making of the heart-team between coronary artery bypass grafting or percutaneous coronary intervention (PCI) in patients with left main or three-vessel coronary artery disease. This study aims to investigate the long-term predictive value of SSII for all-cause mortality in patients with one- or two-vessel disease undergoing PCI. Methods: A total of 628 patients (76% men, mean age: 61±10 years) undergoing PCI due to stable angina pectoris (43%) or acute coronary syndrome (57%), included between January 2008 and June 2013, were eligible for the current study. SSII was calculated using the original SYNTAX score website (www.syntaxscore.com). Cox regression analysis was used to assess the association between continuous SSII and long-term all-cause mortality. The area under the receiver-operating characteristic curve was used to assess the performance of SSII. Results: SSII ranged from 6.6 to 58.2 (median: 20.4, interquartile range: 16.1–26.8). In multivariable analysis, SSII proved to be an independent significant predictor for 4.5-year mortality (hazard ratio per point increase: 1.10; 95% confidence interval: 1.07–1.13; p

Suggested Citation

  • Maxime M Vroegindewey & Anne-Sophie Schuurman & Rohit M Oemrawsingh & Robert-Jan van Geuns & Isabella Kardys & Jurgen Ligthart & Joost Daemen & Eric Boersma & Patrick W Serruys & K Martijn Akkerhuis, 2018. "SYNTAX score II predicts long-term mortality in patients with one- or two-vessel disease," PLOS ONE, Public Library of Science, vol. 13(7), pages 1-9, July.
    • Handle: RePEc:plo:pone00:0200076
    DOI: 10.1371/journal.pone.0200076
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