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Low serum sodium levels at hospital admission: Outcomes among 2.3 million hospitalized patients

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  • Saleem Al Mawed
  • V Shane Pankratz
  • Kelly Chong
  • Matthew Sandoval
  • Maria-Eleni Roumelioti
  • Mark Unruh

Abstract

Background: Hyponatremia is the most common electrolyte disorder among hospitalized patients. Controversies still exist over the relationship between hyponatremia and outcomes of hospitalized patients. Methods: To analyze the association of low serum sodium levels at hospital admission with in-hospital mortality and patient disposition and to compare the distribution of the risk of death associated with hyponatremia across the lifespan of hospitalized patients, we conducted an observational study of 2.3 million patients using data extracted from the Cerner Health Facts database between 2000 and 2014. Logistic regression models were used in the analyses. Results: At hospital admission 14.4% of hospitalized patients had serum sodium levels [Na]

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  • Saleem Al Mawed & V Shane Pankratz & Kelly Chong & Matthew Sandoval & Maria-Eleni Roumelioti & Mark Unruh, 2018. "Low serum sodium levels at hospital admission: Outcomes among 2.3 million hospitalized patients," PLOS ONE, Public Library of Science, vol. 13(3), pages 1-17, March.
    • Handle: RePEc:plo:pone00:0194379
    DOI: 10.1371/journal.pone.0194379
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