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Long-term intra-individual reproducibility of heart rate dynamics during exercise and recovery in the UK Biobank cohort

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  • Michele Orini
  • Andrew Tinker
  • Patricia B Munroe
  • Pier D Lambiase

Abstract

Background: The heart rate (HR) response to exercise provides useful information about the autonomic function and has prognostic value, but its reproducibility over a long period of time, a critical requirement for using it as a clinical biomarker, is undetermined. Aim: To determine the intra-individual reproducibility of HR dynamics during sub-maximum exercise and one minute recovery. Methods: 1187 individuals from the Cardio physical fitness assessment test of the UK Biobank repeated a standard exercise stress test twice (recall time 34.2 ± 2.8 months) and were prospectively studied. Results: 821 individuals complied with inclusion criteria for reproducibility analysis, including peak workload differences between assessments ≤10 W. Intra-individual correlation between HR profile during the first and the second assessment was very high and higher than inter-individual correlation (0.92±0.08 vs 0.87±0.11, p

Suggested Citation

  • Michele Orini & Andrew Tinker & Patricia B Munroe & Pier D Lambiase, 2017. "Long-term intra-individual reproducibility of heart rate dynamics during exercise and recovery in the UK Biobank cohort," PLOS ONE, Public Library of Science, vol. 12(9), pages 1-17, September.
    • Handle: RePEc:plo:pone00:0183732
    DOI: 10.1371/journal.pone.0183732
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