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Ranking 93 health interventions for low- and middle-income countries by cost-effectiveness

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  • Susan Horton
  • Hellen Gelband
  • Dean Jamison
  • Carol Levin
  • Rachel Nugent
  • David Watkins

Abstract

Background: Cost-effectiveness rankings of health interventions are useful inputs for national healthcare planning and budgeting. Previous comprehensive rankings for low- and middle- income countries were undertaken in 2005 and 2006, accompanying the development of strategies for the Millennium Development Goals. We update the rankings using studies published since 2000, as strategies are being considered for the Sustainable Development Goals. Methods: Expert systematic searches of the literature were undertaken for a broad range of health interventions. Cost-effectiveness results using Disability Adjusted Life-Years (DALYs) as the health outcome were standardized to 2012 US dollars. Results: 149 individual studies of 93 interventions qualified for inclusion. Interventions for Reproductive, Maternal, Newborn and Child Health accounted for 37% of interventions, and major infectious diseases (AIDS, TB, malaria and neglected tropical diseases) for 24%, consistent with the priorities of the Millennium Development Goals. More than half of the interventions considered cost less than $200 per DALY and hence can be considered for inclusion in Universal Health Care packages even in low-income countries. Discussion: Important changes have occurred in rankings since 2006. Priorities have changed as a result of new technologies, new methods for changing behavior, and significant price changes for some vaccines and drugs. Achieving the Sustainable Development Goals will require LMICs to study a broader range of health interventions, particularly in adult health. Some interventions are no longer studied, in some cases because they have become usual care, in other cases because they are no longer relevant. Updating cost-effectiveness rankings on a regular basis is potentially a valuable exercise.

Suggested Citation

  • Susan Horton & Hellen Gelband & Dean Jamison & Carol Levin & Rachel Nugent & David Watkins, 2017. "Ranking 93 health interventions for low- and middle-income countries by cost-effectiveness," PLOS ONE, Public Library of Science, vol. 12(8), pages 1-12, August.
  • Handle: RePEc:plo:pone00:0182951
    DOI: 10.1371/journal.pone.0182951
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    References listed on IDEAS

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    1. Don Husereau & Michael Drummond & Stavros Petrou & Chris Carswell & David Moher & Dan Greenberg & Federico Augustovski & Andrew Briggs & Josephine Mauskopf & Elizabeth Loder, 2013. "Consolidated Health Economic Evaluation Reporting Standards (CHEERS) Statement," PharmacoEconomics, Springer, vol. 31(5), pages 361-367, May.
    2. Jessica Ochalek & James Lomas & Karl Claxton, 2015. "Cost per DALY averted thresholds for low- and middle-income countries: evidence from cross country data," Working Papers 122cherp, Centre for Health Economics, University of York.
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    1. Thomas, Ranjeeta & Burger, Ronelle & Hauck, Katharina, 2018. "Richer, wiser and in better health? The socioeconomic gradient in hypertension prevalence, unawareness and control in South Africa," Social Science & Medicine, Elsevier, vol. 217(C), pages 18-30.
    2. Aisha Ummi Jibrin Isah & Obinna Ikechukwu Ekwunife & Izuchukwu Loveth Ejie & Olena Mandrik, 2020. "Effects of nutritional supplements on the re-infection rate of soil-transmitted helminths in school-age children: A systematic review and meta-analysis," PLOS ONE, Public Library of Science, vol. 15(8), pages 1-20, August.
    3. Okeke, Edward N. & Abubakar, Isa S., 2020. "Healthcare at the beginning of life and child survival: Evidence from a cash transfer experiment in Nigeria," Journal of Development Economics, Elsevier, vol. 143(C).
    4. Alireza Mahboub-Ahari & Abolghasem Pourreza & Ali Akbari Sari & Trevor A Sheldon & Maryam Moeeni, 2019. "Private and social time preference for health outcomes: A general population survey in Iran," PLOS ONE, Public Library of Science, vol. 14(2), pages 1-13, February.

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