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Drug-class-specific changes in the volume and cost of antidiabetic medications in Poland between 2012 and 2015

Author

Listed:
  • Andrzej Śliwczyński
  • Melania Brzozowska
  • Andrzej Jacyna
  • Petre Iltchev
  • Tymoteusz Iwańczuk
  • Waldemar Wierzba
  • Michał Marczak
  • Katarzyna Orlewska
  • Piotr Szymański
  • Ewa Orlewska

Abstract

Aim: to investigate the drug-class-specific changes in the volume and cost of antidiabetic medications in Poland in 2012–2015. Methods: This retrospective analysis was conducted based on the National Health Fund database covering an entire Polish population. The volume of antidiabetic medications is reported according to ATC/DDD methodology, costs—in current international dollars, based on purchasing power parity. Results: During a 4-year observational period the number of patients, consumption of antidiabetic drugs and costs increased by 17%, 21% and 20%, respectively. Biguanides are the basic diabetes medication with a 39% market share. The insulin market is still dominated by human insulins, new antidiabetics (incretins, thiazolidinediones) are practically absent. Insulins had the largest share in diabetes medications expenditures (67% in 2015). The increase in antidiabetic medications costs over the analysed period of time was mainly caused by the increased use of insulin analogues. Conclusions: The observed tendencies correspond to the evidence-based HTA recommendations. The reimbursement status, the ratio of cost to clinical outcomes and data on the long-term safety have a deciding impact on how a drug is used.

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  • Andrzej Śliwczyński & Melania Brzozowska & Andrzej Jacyna & Petre Iltchev & Tymoteusz Iwańczuk & Waldemar Wierzba & Michał Marczak & Katarzyna Orlewska & Piotr Szymański & Ewa Orlewska, 2017. "Drug-class-specific changes in the volume and cost of antidiabetic medications in Poland between 2012 and 2015," PLOS ONE, Public Library of Science, vol. 12(6), pages 1-11, June.
    • Handle: RePEc:plo:pone00:0178764
    DOI: 10.1371/journal.pone.0178764
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    Cited by:

    1. Rättö, Hanna & Kurko, Terhi & Martikainen, Jaana E. & Aaltonen, Katri, 2021. "The impact of a co-payment increase on the consumption of type 2 antidiabetics – A nationwide interrupted time series analysis," Health Policy, Elsevier, vol. 125(9), pages 1166-1172.

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