IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0168399.html
   My bibliography  Save this article

HIV Clinical Pathway: A New Approach to Combine Guidelines and Sustainability of Anti-Retroviral Treatment in Italy

Author

Listed:
  • Davide Croce
  • Adriano Lazzarin
  • Giuliano Rizzardini
  • Nicola Gianotti
  • Francesca Scolari
  • Emanuela Foglia
  • Elisabetta Garagiola
  • Elena Ricci
  • Teresa Bini
  • Tiziana Quirino
  • Paolo Viganò
  • Tiziana Re
  • Antonella D’Arminio Monforte
  • Paolo Bonfanti

Abstract

The present article describes the case study of a “real world” HIV practice within the debate concerning the strategic role of Clinical Governance (CG) tools in the management of a National Healthcare System’s sustainability. The study aimed at assessing the impact of a Clinical Pathway (CP) implementation, required by the Regional Healthcare Service, in terms of effectiveness (virological and immunological conditions) and efficiency (economic resources absorption), from the budget holder perspective. Data derived from a multi-centre cohort of patients treated in 6 Hospitals that provided care to approximately 42% of the total HIV+ patients, in Lombardy Region, Italy. Two phases were compared: Pre-CP (2009–2010) vs. Post-CP implementation (2011–2012). All HIV infected adults, observed in the participating hospitals during the study periods, were enrolled and stratified into the 3 categories defined by the Regional CP: first-line, switch for toxicity/other, and switch for failure. The study population was composed of 1,284 patients (Pre-CP phase) and 1,135 patients (Post-CP phase). The results showed that the same level of virological and immunological effectiveness was guaranteed to HIV+ patients: 81.2% of Pre-CP phase population and 83.2% of Post-CP phase population had undetectable HIV-RNA (defined as

Suggested Citation

  • Davide Croce & Adriano Lazzarin & Giuliano Rizzardini & Nicola Gianotti & Francesca Scolari & Emanuela Foglia & Elisabetta Garagiola & Elena Ricci & Teresa Bini & Tiziana Quirino & Paolo Viganò & Tizi, 2016. "HIV Clinical Pathway: A New Approach to Combine Guidelines and Sustainability of Anti-Retroviral Treatment in Italy," PLOS ONE, Public Library of Science, vol. 11(12), pages 1-12, December.
    • Handle: RePEc:plo:pone00:0168399
    DOI: 10.1371/journal.pone.0168399
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0168399
    Download Restriction: no
    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0168399&type=printable
    Download Restriction: no
    File URL: https://libkey.io/10.1371/journal.pone.0168399?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Elisabetta Garagiola & Emanuela Foglia & Lucrezia Ferrario & Giovanni Cenderello & Antonio Di Biagio & Barbara Menzaghi & Giuliano Rizzardini & Davide Croce, 2020. "HTA and HIV: The Case of Dual NRTI Backbones in the Italian Setting," IJERPH, MDPI, vol. 17(23), pages 1-17, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0168399. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.