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The Effect of HIV and the Modifying Effect of Anti-Retroviral Therapy (ART) on Body Mass Index (BMI) and Blood Pressure Levels in Rural South Africa

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  • Andrea B Feigl
  • David E Bloom
  • Goodarz Danaei
  • Deenan Pillay
  • Joshua A Salomon
  • Frank Tanser
  • Till W Bärnighausen

Abstract

Background: High BMI and blood pressure are leading chronic disease risk factors in South Africa. Longterm effects of HIV and ART on adiposity and blood pressure are poorly understood, and direct comparisons of risk factor trajectories in HIV- versus HIV+ populations are rare. Methods: In 2003 and 2010, height, weight, and blood pressure were recorded in a study population (n = 505) in KwaZulu-Natal, South Africa (30% adult HIV prevalence). We modeled change in BMI and BP longitudinally in HIV- individuals (n = 315), seroconverters (n = 32), HIV+ patients not on ART (HIV+ART−; n = 52), HIV+ patients on ART for 0–

Suggested Citation

  • Andrea B Feigl & David E Bloom & Goodarz Danaei & Deenan Pillay & Joshua A Salomon & Frank Tanser & Till W Bärnighausen, 2016. "The Effect of HIV and the Modifying Effect of Anti-Retroviral Therapy (ART) on Body Mass Index (BMI) and Blood Pressure Levels in Rural South Africa," PLOS ONE, Public Library of Science, vol. 11(8), pages 1-15, August.
    • Handle: RePEc:plo:pone00:0158264
    DOI: 10.1371/journal.pone.0158264
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