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Assessment of Open-Angle Glaucoma Peripapillary and Macular Choroidal Thickness Using Swept-Source Optical Coherence Tomography (SS-OCT)

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  • Yong Ju Song
  • Young Kook Kim
  • Jin Wook Jeoung
  • Ki Ho Park

Abstract

Objective: To compare peripapillary and macular choroidal thickness (PCT and MCT) between open-angle glaucoma (OAG) and normal controls using swept-source optical coherence tomography (SS-OCT), and to evaluate global and localized relationships between choroidal thickness and various factors in OAG, also using SS-OCT. Methods: In this cross-sectional comparative study, 134 OAG patients and 73 normal controls were examined. PCT (global, 12 clock-hour sectors), MCT (global, six sectors) were measured by SS-OCT. The difference in choroidal thickness between the OAG patients and the normal controls was analyzed. The relationships between choroidal thickness and various factors including age, sex, spherical equivalent (SE), axial length (AXL), central corneal thickness (CCT), intraocular pressure (IOP), peripapillary retinal nerve fiber layer thickness (pRNFLT), visual field mean deviation (MD), ganglion cell-inner plexiform layer thickness (GCIPLT), and disc area were analyzed by univariate and multivariate linear regression. Global and regional analyses were performed in 12 segments of the peripapillary circle and in six sectors of the macula. Results: There were significant differences in global PCT and MCT between the OAG patients and the normal controls (115.22±41.17 vs. 138.89±44.70, P

Suggested Citation

  • Yong Ju Song & Young Kook Kim & Jin Wook Jeoung & Ki Ho Park, 2016. "Assessment of Open-Angle Glaucoma Peripapillary and Macular Choroidal Thickness Using Swept-Source Optical Coherence Tomography (SS-OCT)," PLOS ONE, Public Library of Science, vol. 11(6), pages 1-12, June.
    • Handle: RePEc:plo:pone00:0157333
    DOI: 10.1371/journal.pone.0157333
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    Cited by:

    1. Hirokazu Kojima & Kazuyuki Hirooka & Shozo Sonoda & Taiji Sakamoto & Yoshiaki Kiuchi, 2019. "Changes in choroidal area following trabeculectomy: Long-term effect of intraocular pressure reduction," PLOS ONE, Public Library of Science, vol. 14(3), pages 1-11, March.
    2. Hirokazu Kojima & Kazuyuki Hirooka & Eri Nitta & Shozo Sonoda & Taiji Sakamoto & Yoshiaki Kiuchi, 2020. "Assessment of primary open-angle glaucoma peripapillary and macular choroidal area using enhanced depth imaging optical coherence tomography," PLOS ONE, Public Library of Science, vol. 15(4), pages 1-10, April.

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