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Galactomannan Testing and the Incidence of Invasive Pulmonary Aspergillosis: A 10-Year Nationwide Population-Based Study in Taiwan

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  • Kuo-Shao Sun
  • Ching-Fang Tsai
  • Solomon Chih-Cheng Chen
  • Yih-Yuan Chen
  • Wan-Chun Huang

Abstract

Background: The clinical impact of the galactomannan (GM) test for the diagnosis of invasive pulmonary aspergillosis (IPA) is controversial. Our study evaluated the incidence and trends of IPA and GM testing in patients with aspergillus infections. Methods: We conducted a nationwide inpatient population study using the Taiwan National Health Insurance Research Database. A total of 346 IPA (62.14% male) patients from the years 2002 to 2011 were identified for inclusion in the study. Results: The average incidence of IPA was 1.51 per million person-years. Over the study period, we observed an increasing trend from 0.94 to 2.06 per million person-years (P

Suggested Citation

  • Kuo-Shao Sun & Ching-Fang Tsai & Solomon Chih-Cheng Chen & Yih-Yuan Chen & Wan-Chun Huang, 2016. "Galactomannan Testing and the Incidence of Invasive Pulmonary Aspergillosis: A 10-Year Nationwide Population-Based Study in Taiwan," PLOS ONE, Public Library of Science, vol. 11(2), pages 1-9, February.
    • Handle: RePEc:plo:pone00:0149964
    DOI: 10.1371/journal.pone.0149964
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