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Body Mass Index and Decline of Cognitive Function

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  • Sujin Kim
  • Yongjoo Kim
  • Sang Min Park

Abstract

Background: The association between body mass index (BMI) and cognitive function is a public health issue. This study investigated the relationship between obesity and cognitive impairment which was assessed by the Korean version of the Mini-mental state examination (K-MMSE) among mid- and old-aged people in South Korea. Methods: A cohort of 5,125 adults, age 45 or older with normal cognitive function (K-MMSE≥24) at baseline (2006), was derived from the Korean Longitudinal Study of Aging (KLoSA) 2006~2012. The association between baseline BMI and risk of cognitive impairment was assessed using multiple logistic regression models. We also assessed baseline BMI and change of cognitive function over the 6-year follow-up using multiple linear regressions. Results: During the follow-up, 358 cases of severe cognitive impairment were identified. Those with baseline BMI≥25 kg/m2 than normal-weight (18.5≤BMI

Suggested Citation

  • Sujin Kim & Yongjoo Kim & Sang Min Park, 2016. "Body Mass Index and Decline of Cognitive Function," PLOS ONE, Public Library of Science, vol. 11(2), pages 1-14, February.
  • Handle: RePEc:plo:pone00:0148908
    DOI: 10.1371/journal.pone.0148908
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