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Factors Influencing Intraocular Pressure Changes after Laser In Situ Keratomileusis with Flaps Created by Femtosecond Laser or Mechanical Microkeratome

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  • Meng-Yin Lin
  • David C K Chang
  • Yun-Dun Shen
  • Yen-Kuang Lin
  • Chang-Ping Lin
  • I-Jong Wang

Abstract

The aim of this study is to describe factors that influence the measured intraocular pressure (IOP) change and to develop a predictive model after myopic laser in situ keratomileusis (LASIK) with a femtosecond (FS) laser or a microkeratome (MK). We retrospectively reviewed preoperative, intraoperative, and 12-month postoperative medical records in 2485 eyes of 1309 patients who underwent LASIK with an FS laser or an MK for myopia and myopic astigmatism. Data were extracted, such as preoperative age, sex, IOP, manifest spherical equivalent (MSE), central corneal keratometry (CCK), central corneal thickness (CCT), and intended flap thickness and postoperative IOP (postIOP) at 1, 6 and 12 months. Linear mixed model (LMM) and multivariate linear regression (MLR) method were used for data analysis. In both models, the preoperative CCT and ablation depth had significant effects on predicting IOP changes in the FS and MK groups. The intended flap thickness was a significant predictor only in the FS laser group (P

Suggested Citation

  • Meng-Yin Lin & David C K Chang & Yun-Dun Shen & Yen-Kuang Lin & Chang-Ping Lin & I-Jong Wang, 2016. "Factors Influencing Intraocular Pressure Changes after Laser In Situ Keratomileusis with Flaps Created by Femtosecond Laser or Mechanical Microkeratome," PLOS ONE, Public Library of Science, vol. 11(1), pages 1-11, January.
    • Handle: RePEc:plo:pone00:0147699
    DOI: 10.1371/journal.pone.0147699
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