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Association between Diabetes and Risk of Aortic Dissection: A Case-Control Study in a Chinese Population

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Listed:
  • Xingwei He
  • Xintian Liu
  • Wanjun Liu
  • Bei Wang
  • Yujian Liu
  • Zhuxi Li
  • Tao Wang
  • Rong Tan
  • Bo Gao
  • Hesong Zeng

Abstract

Background: It is well-recognized that diabetes represents a powerful independent risk factor for cardiovascular diseases. However, very few studies have investigated the relationship between diabetes and risk of aortic dissection (AD). Aim: The aim of this case-control study was to evaluate the association between diabetes and risk of AD in Chinese population. Methods: A hospital-based case-control study, consisting of 2160 AD patients and 4320 controls, was conducted in a Chinese population. Demographic, clinical characteristics and risk factors were collected. Diabetes rate of patients with overall AD, Stanford type A AD and type B AD group was compared with that of corresponding matched control groups. Logistic regression analysis was used to estimate the odds ratios (OR) and 95% confidence intervals (95% CI) for relationship between diabetes and AD risk. Results: The prevalence of diabetes was lower in AD cases than that of control subjects, whether it is the overall AD, type A AD or type B AD group (4.7% vs. 10.0%, 2.9% vs. 8.8%, 5.9% vs. 10.9%, all P

Suggested Citation

  • Xingwei He & Xintian Liu & Wanjun Liu & Bei Wang & Yujian Liu & Zhuxi Li & Tao Wang & Rong Tan & Bo Gao & Hesong Zeng, 2015. "Association between Diabetes and Risk of Aortic Dissection: A Case-Control Study in a Chinese Population," PLOS ONE, Public Library of Science, vol. 10(11), pages 1-10, November.
  • Handle: RePEc:plo:pone00:0142697
    DOI: 10.1371/journal.pone.0142697
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