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Health Gains and Financial Protection from Pneumococcal Vaccination and Pneumonia Treatment in Ethiopia: Results from an Extended Cost-Effectiveness Analysis

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  • Kjell Arne Johansson
  • Solomon Tessema Memirie
  • Clint Pecenka
  • Dean T Jamison
  • Stéphane Verguet

Abstract

Background: Pneumonia and pneumococcal disease cause a large disease burden in resource-constrained settings. We pursue an extended cost-effectiveness analysis (ECEA) of two fully publicly financed interventions in Ethiopia: pneumococcal vaccination for newborns and pneumonia treatment for under-five children in Ethiopia. Methods: We apply ECEA methods and estimate the program impact on: (1) government program costs; (2) pneumonia and pneumococcal deaths averted; (3) household expenses related to pneumonia/pneumococcal disease treatment averted; (4) prevention of household medical impoverishment measured by an imputed money-metric value of financial risk protection; and (5) distributional consequences across the wealth strata of the country population. Available epidemiological and cost data from Ethiopia are applied and the two interventions are assessed separately at various incremental coverage levels. Results: Scaling-up pneumococcal vaccines at around 40% coverage would cost about $11.5 million and avert about 2090 child deaths annually, while a 10% increase of pneumonia treatment to all children under 5 years of age would cost about $13.9 million and avert 2610 deaths annually. Health benefits of the two interventions publicly financed would be concentrated among the bottom income quintile, where 30–40% of all deaths averted would be expected to occur in the poorest quintile. In sum, the two interventions would eliminate a total of $2.4 million of private household expenditures annually, where the richest quintile benefits from around 30% of the total private expenditures averted. The financial risk protection benefits would be largely concentrated among the bottom income quintile. The results are most sensitive to variations in vaccine price, population size, number of deaths due to pneumonia, efficacy of interventions and out-of-pocket copayment share. Conclusions: Vaccine and treatment interventions for children, as shown with the illustrative examples of pneumococcal vaccine and pneumonia treatment, can bring large health and financial benefits to households in Ethiopia, most particularly among the poorest socio-economic groups.

Suggested Citation

  • Kjell Arne Johansson & Solomon Tessema Memirie & Clint Pecenka & Dean T Jamison & Stéphane Verguet, 2015. "Health Gains and Financial Protection from Pneumococcal Vaccination and Pneumonia Treatment in Ethiopia: Results from an Extended Cost-Effectiveness Analysis," PLOS ONE, Public Library of Science, vol. 10(12), pages 1-16, December.
  • Handle: RePEc:plo:pone00:0142691
    DOI: 10.1371/journal.pone.0142691
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    References listed on IDEAS

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    1. McClellan, Mark & Skinner, Jonathan, 2006. "The incidence of Medicare," Journal of Public Economics, Elsevier, vol. 90(1-2), pages 257-276, January.
    2. Dean T. Jamison & Joel G. Breman & Anthony R. Measham & George Alleyne & Mariam Claeson & David B. Evans & Prabhat Jha & Ann Mills & Philip Musgrove, 2006. "Disease Control Priorities in Developing Countries, Second Edition," World Bank Publications - Books, The World Bank Group, number 7242.
    3. Salem, A B Z & Mount, T D, 1974. "A Convenient Descriptive Model of Income Distribution: The Gamma Density," Econometrica, Econometric Society, vol. 42(6), pages 1115-1127, November.
    4. World Bank, 2005. "Ethiopia : A Country Status Report on Health and Poverty, Volume 2, Main Report," World Bank Publications - Reports 8687, The World Bank Group.
    5. Sun-Young Kim & Sue Goldie, 2008. "Cost-Effectiveness Analyses of Vaccination Programmes," PharmacoEconomics, Springer, vol. 26(3), pages 191-215, March.
    6. World Bank, 2014. "World Development Indicators 2014," World Bank Publications - Books, The World Bank Group, number 18237.
    7. World Bank, 2005. "Nigeria : Health, Nutrition, and Population, Country Status Report, Volume 2, Main Report," World Bank Publications - Reports 8804, The World Bank Group.
    8. Philip Ayieko & Ulla K Griffiths & Moses Ndiritu & Jennifer Moisi & Isaac K Mugoya & Tatu Kamau & Mike English & J Anthony G Scott, 2013. "Assessment of Health Benefits and Cost-Effectiveness of 10-Valent and 13-Valent Pneumococcal Conjugate Vaccination in Kenyan Children," PLOS ONE, Public Library of Science, vol. 8(6), pages 1-9, June.
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