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Predictors for Stroke and Death in Non-Anticoagulated Asian Patients with Atrial Fibrillation: The Fushimi AF Registry

Author

Listed:
  • Yasuhiro Hamatani
  • Yugo Yamashita
  • Masahiro Esato
  • Yeong-Hwa Chun
  • Hikari Tsuji
  • Hiromichi Wada
  • Koji Hasegawa
  • Mitsuru Abe
  • Gregory Y H Lip
  • Masaharu Akao

Abstract

Background: Atrial fibrillation (AF) increases the risk of stroke and death. Data on the predictors for stroke and death in ‘real-world’ AF patients are limited, especially from large prospective Asian cohorts. Methods: The Fushimi AF Registry is a community-based prospective survey designed to enroll all AF patients who visited the participating medical institutions in Fushimi-ku, Kyoto, Japan. Follow-up data were available for 3,304 patients (median follow-up period 741 days). We explored the predictors for ‘death, stroke, and systemic embolism (SE)’ during follow-up in 1,541 patients not receiving oral anticoagulants (OAC) at baseline. Results: The mean age was 73.1 ± 12.5 years, and 673 (44%) patients were female. The mean CHADS2 and CHA2DS2-VASc scores were 1.76 and 3.08, respectively. Cumulative events were as follows: stroke/SE in 61 (4%) and death in 230 (15%), respectively. On multivariate analysis, advanced age (hazard ratio (HR): 1.68, 95% confidence interval (CI): 1.24–2.29), underweight (body mass index

Suggested Citation

  • Yasuhiro Hamatani & Yugo Yamashita & Masahiro Esato & Yeong-Hwa Chun & Hikari Tsuji & Hiromichi Wada & Koji Hasegawa & Mitsuru Abe & Gregory Y H Lip & Masaharu Akao, 2015. "Predictors for Stroke and Death in Non-Anticoagulated Asian Patients with Atrial Fibrillation: The Fushimi AF Registry," PLOS ONE, Public Library of Science, vol. 10(11), pages 1-14, November.
    • Handle: RePEc:plo:pone00:0142394
    DOI: 10.1371/journal.pone.0142394
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