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Neurotranscriptomics: The Effects of Neonatal Stimulus Deprivation on the Rat Pineal Transcriptome

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  • Stephen W Hartley
  • Steven L Coon
  • Luis E Savastano
  • James C Mullikin
  • NISC Comparative Sequencing Program
  • Cong Fu
  • David C Klein

Abstract

The term neurotranscriptomics is used here to describe genome-wide analysis of neural control of transcriptomes. In this report, next-generation RNA sequencing was using to analyze the effects of neonatal (5-days-of-age) surgical stimulus deprivation on the adult rat pineal transcriptome. In intact animals, more than 3000 coding genes were found to exhibit differential expression (adjusted-p

Suggested Citation

  • Stephen W Hartley & Steven L Coon & Luis E Savastano & James C Mullikin & NISC Comparative Sequencing Program & Cong Fu & David C Klein, 2015. "Neurotranscriptomics: The Effects of Neonatal Stimulus Deprivation on the Rat Pineal Transcriptome," PLOS ONE, Public Library of Science, vol. 10(9), pages 1-16, September.
    • Handle: RePEc:plo:pone00:0137548
    DOI: 10.1371/journal.pone.0137548
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