IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0132488.html
   My bibliography  Save this article

Impact of the Preoperative Controlling Nutritional Status (CONUT) Score on the Survival after Curative Surgery for Colorectal Cancer

Author

Listed:
  • Yasuhito Iseki
  • Masatsune Shibutani
  • Kiyoshi Maeda
  • Hisashi Nagahara
  • Hiroshi Ohtani
  • Kenji Sugano
  • Tetsuro Ikeya
  • Kazuya Muguruma
  • Hiroaki Tanaka
  • Takahiro Toyokawa
  • Katsunobu Sakurai
  • Kosei Hirakawa

Abstract

Background: Recently, the preoperative immune-nutritional status has been reported to correlate with the survival rate in patients with colorectal cancer (CRC). However, there have been no reports on the relationship between the controlling nutritional status (CONUT) score and the clinical outcome after curative surgery for CRC. We herein evaluated the prognostic significance of the CONUT score in patients with CRC, and then compared the accuracy of the CONUT score and the prognostic nutritional index (PNI) as a predictor of survival. Methods: We retrospectively reviewed a database of 204 patients who underwent curative surgery for Stage II/III CRC. Patients were divided into two groups according to the CONUT score and the PNI. Results: The five-year cancer-specific survival (CSS) rate was significantly higher at 92.7% in the low CONUT group, compared to a rate of 81.0% in the high CONUT group (p=0.0016). The five-year CSS was 71.2% in the low PNI group and 92.3% in the high PNI group, which showed a significant difference (p=0.0155). A multivariate analysis showed that lymph node metastasis and the CONUT score were independent risk factors for CSS. Conclusion: This study suggested that the CONUT score is a strong independent predictor of the survival among CRC patients.

Suggested Citation

  • Yasuhito Iseki & Masatsune Shibutani & Kiyoshi Maeda & Hisashi Nagahara & Hiroshi Ohtani & Kenji Sugano & Tetsuro Ikeya & Kazuya Muguruma & Hiroaki Tanaka & Takahiro Toyokawa & Katsunobu Sakurai & Kos, 2015. "Impact of the Preoperative Controlling Nutritional Status (CONUT) Score on the Survival after Curative Surgery for Colorectal Cancer," PLOS ONE, Public Library of Science, vol. 10(7), pages 1-13, July.
    • Handle: RePEc:plo:pone00:0132488
    DOI: 10.1371/journal.pone.0132488
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0132488
    Download Restriction: no
    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0132488&type=printable
    Download Restriction: no
    File URL: https://libkey.io/10.1371/journal.pone.0132488?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Hironori Mizuno & Norihiro Yuasa & Eiji Takeuchi & Hideo Miyake & Hidemasa Nagai & Yuichiro Yoshioka & Kanji Miyata, 2019. "Blood cell markers that can predict the long-term outcomes of patients with colorectal cancer," PLOS ONE, Public Library of Science, vol. 14(8), pages 1-15, August.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0132488. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.