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Safety and Efficacy of Thermal Ablation for Small Renal Masses in Solitary Kidney: Evidence from Meta-Analysis of Comparative Studies

Author

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  • Quancheng Yang
  • Fanzheng Meng
  • Kai Li
  • Tong Wang
  • Qingyuan Nie
  • Zi Che
  • Min Liu
  • Yan Sun
  • Lin Zhao

Abstract

Objective: To evaluate comparative renal functional preservation, perioperative and oncologic outcomes, and complications of thermal ablation (TA) versus partial nephrectomy (PN) in management of Small renal masses (SRMs) in solitary kidney. Methods and Findings: Medline, Embase, Web of Science and the Cochrane Library were systematically searched. A meta-analysis for comparative studies comparing TA with PN was performed. According to predefined inclusion criteria, seven datasets were identified from 8 observational studies including a total of 628 patients. Cumulated data showed the changes of creatinine (p=0.02) and estimated glomerular filtration rate (eGFR) (p

Suggested Citation

  • Quancheng Yang & Fanzheng Meng & Kai Li & Tong Wang & Qingyuan Nie & Zi Che & Min Liu & Yan Sun & Lin Zhao, 2015. "Safety and Efficacy of Thermal Ablation for Small Renal Masses in Solitary Kidney: Evidence from Meta-Analysis of Comparative Studies," PLOS ONE, Public Library of Science, vol. 10(6), pages 1-12, June.
    • Handle: RePEc:plo:pone00:0131290
    DOI: 10.1371/journal.pone.0131290
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