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Meta-Analysis Comparing Zero-Profile Spacer and Anterior Plate in Anterior Cervical Fusion

Author

Listed:
  • Jun Dong
  • Meng Lu
  • Teng Lu
  • Baobao Liang
  • Junkui Xu
  • Jun Zhou
  • Hongjun Lv
  • Jie Qin
  • Xuan Cai
  • Sihua Huang
  • Haopeng Li
  • Dong Wang
  • Xijing He

Abstract

Background: Anterior plate fusion is an effective procedure for the treatment of cervical spinal diseases but is accompanied by a high incidence of postoperative dysphagia. A zero profile (Zero-P) spacer is increasingly being used to reduce postoperative dysphagia and other potential complications associated with surgical intervention. Studies comparing the Zero-P spacer and anterior plate have reported conflicting results. Methodology: A meta-analysis was conducted to compare the safety, efficacy, radiological outcomes and complications associated with the use of a Zero-P spacer versus an anterior plate in anterior cervical spine fusion for the treatment of cervical spinal disease. We comprehensively searched PubMed, Embase, the Cochrane Library and other databases and performed a meta-analysis of all randomized controlled trials (RCTs) and prospective or retrospective comparative studies assessing the two techniques. Results: Ten studies enrolling 719 cervical spondylosis patients were included. The pooled data showed significant differences in the operation time [SMD = –0.58 (95% CI = −0.77 to 0.40, p

Suggested Citation

  • Jun Dong & Meng Lu & Teng Lu & Baobao Liang & Junkui Xu & Jun Zhou & Hongjun Lv & Jie Qin & Xuan Cai & Sihua Huang & Haopeng Li & Dong Wang & Xijing He, 2015. "Meta-Analysis Comparing Zero-Profile Spacer and Anterior Plate in Anterior Cervical Fusion," PLOS ONE, Public Library of Science, vol. 10(6), pages 1-18, June.
    • Handle: RePEc:plo:pone00:0130223
    DOI: 10.1371/journal.pone.0130223
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