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Reproducibility in Echocardiographic Assessment of Diastolic Function in a Population Based Study (The STANISLAS Cohort Study)

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Listed:
  • Zied Frikha
  • Nicolas Girerd
  • Olivier Huttin
  • Pierre Yves Courand
  • Erwan Bozec
  • Arnaud Olivier
  • Zohra Lamiral
  • Faiez Zannad
  • Patrick Rossignol

Abstract

Introduction: There is limited evidence regarding intra-observer and inter-observer variations in echocardiographic measurements of diastolic function. This study aimed to assess this reproducibly within a population-based cohort study. Methods: Sixty subjects in sinus rhythm were randomly selected among 4th visit participants of the STANISLAS Cohort (Lorraine region, France). This 4th examination systematically included M-mode, 2-dimensional, DTI and pulsed-wave Doppler echocardiograms. Reproducibility of variables was studied by intra-class correlation coefficients (ICC) and Bland Altman plots. Results: Our population was on average middle-aged (50 ± 14y), overweight (BMI = 26 ± 6kg/m2) and non-smoking (87%) with a quarter of the participants having self-declared hypertension or treated with anti-hypertensive medication(s). Intra-observer ICC were > 0.90 for all analyzed parameters except for left ventricular ejection fraction (LVEF) which was 0.89 (0.81–0.93). The mean relative intra-observer differences were small and limits of agreement of relative differences were narrow for all considered parameters ( 0.90 for all analyzed parameters except for LVEF (ICC = 0.87) and both mitral and pulmonary A wave duration (0.83 and 0.73 respectively). The mean relative inter-observer differences were

Suggested Citation

  • Zied Frikha & Nicolas Girerd & Olivier Huttin & Pierre Yves Courand & Erwan Bozec & Arnaud Olivier & Zohra Lamiral & Faiez Zannad & Patrick Rossignol, 2015. "Reproducibility in Echocardiographic Assessment of Diastolic Function in a Population Based Study (The STANISLAS Cohort Study)," PLOS ONE, Public Library of Science, vol. 10(4), pages 1-12, April.
    • Handle: RePEc:plo:pone00:0122336
    DOI: 10.1371/journal.pone.0122336
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