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Trends in Cardiac Biomarker Testing in China for Patients with Acute Myocardial Infarction, 2001 to 2011: China PEACE-Retrospective AMI Study

Author

Listed:
  • Lijuan Zhan
  • Frederick A Masoudi
  • Xi Li
  • Shuang Hu
  • Arjun K Venkatesh
  • John A Spertus
  • Zhenqiu Lin
  • Nihar R Desai
  • Jing Li
  • Harlan M Krumholz
  • Lixin Jiang
  • China PEACE Collaborative Group

Abstract

Objectives: To describe trends in the availability of biomarker testing in Chinese hospitals and how practice complies with established standards for the diagnosis of acute myocardial infarction (AMI). Background: Cardiac biomarker testing is standard in high-income countries, but little is known about the availability and use of cardiac biomarker testing in low- and middle-income countries (LMICs) such as China. Methods: Based on a nationally representative sample of Chinese hospitals in 2001, 2006 and 2011, we describe the temporal trends and regional differences in the hospital capability and rates of use of cardiac biomarker testing, as well as the variation in use across hospitals with testing capability, for patients labeled with the diagnosis of AMI. Results: We sampled 175 hospitals (162 participated in the study) and 18,631 AMI admissions. 14,370 patients were included in analysis of biomarker use. The proportion of hospitals with biomarker testing capability was 57.4% in 2001 (25.0% troponin and 32.4% creatine kinase MB fraction (CK-MB) only) and 96.3% (81.4% troponin and 14.9% CK-MB only) in 2011. The proportion of hospitals with troponin testing capability in 2011 was significantly higher in urban compared with rural hospitals (96.8% vs. 71.4%, p

Suggested Citation

  • Lijuan Zhan & Frederick A Masoudi & Xi Li & Shuang Hu & Arjun K Venkatesh & John A Spertus & Zhenqiu Lin & Nihar R Desai & Jing Li & Harlan M Krumholz & Lixin Jiang & China PEACE Collaborative Group, 2015. "Trends in Cardiac Biomarker Testing in China for Patients with Acute Myocardial Infarction, 2001 to 2011: China PEACE-Retrospective AMI Study," PLOS ONE, Public Library of Science, vol. 10(4), pages 1-14, April.
    • Handle: RePEc:plo:pone00:0122237
    DOI: 10.1371/journal.pone.0122237
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