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Instability in the COPD Diagnosis upon Repeat Testing Vary with the Definition of COPD

Author

Listed:
  • Rogelio Perez-Padilla
  • Fernando C Wehrmeister
  • Maria Montes de Oca
  • Maria Victorina Lopez
  • Jose R Jardim
  • Adriana Muino
  • Gonzalo Valdivia
  • Julio Pertuze
  • Ana Maria B Menezes
  • PLATINO group

Abstract

Background: A low FEV1/FVC from post-bronchodilator spirometry is required to diagnose COPD. Both the FEV1 and the FVC can vary over time; therefore, individuals can be given a diagnosis of mild COPD at one visit, but have normal spirometry during the next appointment, even without an intervention. Methods: We analyzed two population-based surveys of adults with spirometry carried out for the same individuals 5-9 years after their baseline examination. We determined the factors associated with a change in the spirometry interpretation from one exam to the next utilizing different criteria commonly used to diagnose COPD. Results: The rate of an inconsistent diagnosis of mild COPD was 11.7% using FEV1/FVC

Suggested Citation

  • Rogelio Perez-Padilla & Fernando C Wehrmeister & Maria Montes de Oca & Maria Victorina Lopez & Jose R Jardim & Adriana Muino & Gonzalo Valdivia & Julio Pertuze & Ana Maria B Menezes & PLATINO group, 2015. "Instability in the COPD Diagnosis upon Repeat Testing Vary with the Definition of COPD," PLOS ONE, Public Library of Science, vol. 10(3), pages 1-13, March.
    • Handle: RePEc:plo:pone00:0121832
    DOI: 10.1371/journal.pone.0121832
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