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Association between Childhood Strabismus and Refractive Error in Chinese Preschool Children

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  • Hui Zhu
  • Jia-Jia Yu
  • Rong-Bin Yu
  • Hui Ding
  • Jing Bai
  • Ji Chen
  • Hu Liu

Abstract

Purpose: To investigate the association between concomitant esotropia or concomitant exotropia and refractive error in preschool children Methods: A population-based sample of 5831 children aged 3 to 6 years was selected from all kindergartens in a representative county (Yuhuatai District, Nanjing, Jiangsu Province) of Nanjing, China. Clinical examinations including ocular alignment, ocular motility, visual acuity, optometry, stereopsis screening, slit lamp examination and fundus examination were performed by trained ophthalmologists and optometrists. Odd ratios (OR) and 95% confidence intervals (95% CI) were calculated to evaluate the association of refractive error with concomitant esotropia and concomitant exotropia. Results: In multivariate logistic regression analysis, concomitant esotropia was associated independently with spherical equivalent anisometropia (OR, 3.15 for 0.50 to = 1.00 D of anisometropia) and hyperopia. There was a severity-dependent association of hyperopia with the development of concomitant esotropia, with ORs increasing from 9.3 for 2.00 to = 5.00 D of hyperopia. Concomitant exotropia was associated with astigmatism (OR, 3.56 for 0.50 to 1.00 D of astigmatism, and 1.9 for

Suggested Citation

  • Hui Zhu & Jia-Jia Yu & Rong-Bin Yu & Hui Ding & Jing Bai & Ji Chen & Hu Liu, 2015. "Association between Childhood Strabismus and Refractive Error in Chinese Preschool Children," PLOS ONE, Public Library of Science, vol. 10(3), pages 1-11, March.
  • Handle: RePEc:plo:pone00:0120720
    DOI: 10.1371/journal.pone.0120720
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    Cited by:

    1. Kyung Eun Han & Seung-Hee Baek & Seung-Hyun Kim & Key Hwan Lim & Epidemiologic Survey Committee of the Korean Ophthalmological Society, 2018. "Prevalence and risk factors of strabismus in children and adolescents in South Korea: Korea National Health and Nutrition Examination Survey, 2008–2011," PLOS ONE, Public Library of Science, vol. 13(2), pages 1-14, February.

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