IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0118592.html
   My bibliography  Save this article

The 3-Second Rule in Hereditary Pure Cerebellar Ataxia: A Synchronized Tapping Study

Author

Listed:
  • Shunichi Matsuda
  • Hideyuki Matsumoto
  • Toshiaki Furubayashi
  • Ritsuko Hanajima
  • Shoji Tsuji
  • Yoshikazu Ugawa
  • Yasuo Terao

Abstract

The ‘3-second rule’ has been proposed based on miscellaneous observations that a time period of around 3 seconds constitutes the fundamental unit of time related to the neuro-cognitive machinery in normal humans. The aim of paper was to investigate the temporal processing in patients with spinocerebellar ataxia type 6 (SCA6) and SCA31, pure cerebellar types of spinocerebellar degeneration, using a synchronized tapping task. Seventeen SCA patients (11 SCA6, 6 SCA31) and 17 normal age-matched volunteers participated. The task required subjects to tap a keyboard in synchrony with sequences of auditory stimuli presented at fixed interstimulus intervals (ISIs) between 200 and 4800 ms. In this task, the subjects required non-motor components to estimate the time of forthcoming tone in addition to motor components to tap. Normal subjects synchronized their taps to the presented tones at shorter ISIs, whereas as the ISI became longer, the normal subjects displayed greater latency between the tone and the tapping (transition zone). After the transition zone, normal subjects pressed the button delayed relative to the tone. On the other hand, SCA patients could not synchronize their tapping with the tone even at shorter ISIs, although they pressed the button delayed relative to the tone earlier than normal subjects did. The earliest time of delayed tapping appearance after the transition zone was 4800 ms in normal subjects but 1800 ms in SCA patients. The span of temporal integration in SCA patients is shortened compared to that in normal subjects. This could represent non-motor cerebellar dysfunction in SCA patients.

Suggested Citation

  • Shunichi Matsuda & Hideyuki Matsumoto & Toshiaki Furubayashi & Ritsuko Hanajima & Shoji Tsuji & Yoshikazu Ugawa & Yasuo Terao, 2015. "The 3-Second Rule in Hereditary Pure Cerebellar Ataxia: A Synchronized Tapping Study," PLOS ONE, Public Library of Science, vol. 10(2), pages 1-13, February.
  • Handle: RePEc:plo:pone00:0118592
    DOI: 10.1371/journal.pone.0118592
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0118592
    Download Restriction: no

    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0118592&type=printable
    Download Restriction: no

    File URL: https://libkey.io/10.1371/journal.pone.0118592?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Dominika Dykiert & Geoff Der & John M Starr & Ian J Deary, 2012. "Age Differences in Intra-Individual Variability in Simple and Choice Reaction Time: Systematic Review and Meta-Analysis," PLOS ONE, Public Library of Science, vol. 7(10), pages 1-23, October.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Andreas W Blomkvist & Fredrik Eika & Martin T Rahbek & Karin D Eikhof & Mette D Hansen & Malene Søndergaard & Jesper Ryg & Stig Andersen & Martin G Jørgensen, 2017. "Reference data on reaction time and aging using the Nintendo Wii Balance Board: A cross-sectional study of 354 subjects from 20 to 99 years of age," PLOS ONE, Public Library of Science, vol. 12(12), pages 1-13, December.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0118592. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.