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Perception of Antiretroviral Generic Medicines: One-Day Survey of HIV-Infected Patients and Their Physicians in France

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Listed:
  • Christine Jacomet
  • Clotilde Allavena
  • Fleur Peyrol
  • Bruno Pereira
  • Laurence Morand Joubert
  • Haleh Bagheri
  • Laurent Cotte
  • Rodolphe Garaffo
  • Laurent Gerbaud
  • Pierre Dellamonica

Abstract

Background: In the interest of cost effectiveness, switching antiretroviral brand name medications to generics is recommended in France since 2013. The study objective was to evaluate the perception of generics per se and antiretroviral generics in HIV-infected patients and their hospital physicians Methods and Findings: 556 out of 703 (79%) adult HIV+ outpatients and 116 physicians in 33 clinics were included in a multicentric cross-sectional survey performed in September 2013. Patients completed a self-questionnaire on their perception and acceptability of generics. Physicians completed a questionnaire on their acceptability of switching antiretroviral to generic. Socio-demographic data, medical history and HIV history were collected. Among the 556 patients with a median HIV duration of 13 years, 77% were France native, 59% in active employment, 100% covered by social insurance, 95% on antiretroviral therapy. Seventy-six percent of the patients accepted generics and 55% trusted them overall. Antiretroviral generics were accepted by 44% of them but only by 17% if the pill burden was going to increase. The factor significantly associated with acceptability of antiretroviral generics was acceptance of generics per se (p

Suggested Citation

  • Christine Jacomet & Clotilde Allavena & Fleur Peyrol & Bruno Pereira & Laurence Morand Joubert & Haleh Bagheri & Laurent Cotte & Rodolphe Garaffo & Laurent Gerbaud & Pierre Dellamonica, 2015. "Perception of Antiretroviral Generic Medicines: One-Day Survey of HIV-Infected Patients and Their Physicians in France," PLOS ONE, Public Library of Science, vol. 10(2), pages 1-13, February.
    • Handle: RePEc:plo:pone00:0117214
    DOI: 10.1371/journal.pone.0117214
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    References listed on IDEAS

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    1. Granlund, David, 2009. "Are private physicians more likely to veto generic substitution of prescribed pharmaceuticals?," Social Science & Medicine, Elsevier, vol. 69(11), pages 1643-1650, December.
    2. Valles, Joan-Antoni & Barreiro, Maica & Cereza, Gloria & Ferro, Juan-Jose & Martinez, Maria-Jose & Escriba, Josep-Maria & Iglesias, Begona & Cucurull, Esther & Barcelo, Estrella AU -, 2003. "A prospective multicenter study of the effect of patient education on acceptability of generic prescribing in general practice," Health Policy, Elsevier, vol. 65(3), pages 269-275, September.
    3. Chong, Chee Ping & March, Geoff & Clark, Alice & Gilbert, Andrew & Hassali, Mohamed Azmi & Bahari, Mohd Baidi, 2011. "A nationwide study on generic medicines substitution practices of Australian community pharmacists and patient acceptance," Health Policy, Elsevier, vol. 99(2), pages 139-148, February.
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    Cited by:

    1. Rwagitinywa, Joseph & Sommet, Agnès & Palmaro, Aurore & Montastruc, Jean-Louis & Lapeyre-Mestre, Maryse, 2018. "Utilization and costs of HIV antiretroviral drugs in Europe during the last ten years: Impact of generic antiretroviral drugs on cost reduction," Health Policy, Elsevier, vol. 122(3), pages 237-242.
    2. Amandine Garcia & Sascha Moore Boffi & Angèle Gayet-Ageron & Nathalie Vernaz, 2019. "Access to unauthorized hepatitis C generics: Perception and knowledge of physicians, pharmacists, patients and non-healthcare professionals," PLOS ONE, Public Library of Science, vol. 14(10), pages 1-14, October.

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