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A Comparison between the EQ-5D and the SF-6D in Patients with Chronic Obstructive Pulmonary Disease (COPD)

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  • Jing Chen
  • Carlos K H Wong
  • Sarah M McGhee
  • Polly K P Pang
  • Wai-Cho Yu

Abstract

Background: The appropriate use of generic preference-based measures determines the accuracy of disease assessment and further decision on healthcare policy using quality adjusted life years. The discriminative capacity of different instruments would differ across disease groups. Our study was to examine the difference in utility scores for COPD patients measured by EQ-5D and SF-6D and to assist the choice of a proper instrument in this disease group. Methods: Differences of mean utility scores of EQ-5D and SF-6D in groups defined by socio-demographic characteristics, comorbidities, health service utilisation and severity of illness were tested using Mann-Whitney test, t-test, Kruskal-Wallis test, Pearson’s correlation coefficient and ANOVA, as appropriate. The discriminative properties of the two instruments were compared against indicators of quality of life using receiver operating characteristic curves. The statistical significance of the area under the curves (AUC) was tested by ANOVA and F-statistics used to compare the efficiency with which each instrument discriminated between disease severity groups. Results: Mean utility scores of EQ-5D and SF-6D were 0.644 and 0.629 respectively in the 154 subjects included in the analysis. EQ-5D scores were significantly higher than SF-6D in groups less severe and these differences corresponded to a minimally important difference of greater than 0.03 (p 0.5 and p

Suggested Citation

  • Jing Chen & Carlos K H Wong & Sarah M McGhee & Polly K P Pang & Wai-Cho Yu, 2014. "A Comparison between the EQ-5D and the SF-6D in Patients with Chronic Obstructive Pulmonary Disease (COPD)," PLOS ONE, Public Library of Science, vol. 9(11), pages 1-9, November.
    • Handle: RePEc:plo:pone00:0112389
    DOI: 10.1371/journal.pone.0112389
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    References listed on IDEAS

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    1. Xinyu Qian & Rachel Lee-Yin Tan & Ling-Hsiang Chuang & Nan Luo, 2020. "Measurement Properties of Commonly Used Generic Preference-Based Measures in East and South-East Asia: A Systematic Review," PharmacoEconomics, Springer, vol. 38(2), pages 159-170, February.
    2. Myung-Jae Hwang & Jong-Hun Kim & Hae-Kwan Cheong, 2020. "Short-Term Impacts of Ambient Air Pollution on Health-Related Quality of Life: A Korea Health Panel Survey Study," IJERPH, MDPI, vol. 17(23), pages 1-11, December.
    3. Yeon Wook Kim & Chang-Hoon Lee & Young Sik Park & Yu-Il Kim & Chul Min Ahn & Ju-Ock Kim & Joo Hun Park & Sang Haak Lee & Jae Yeol Kim & Eun Mi Chun & Tae Hoon Jung & Kwang Ha Yoo, 2015. "Effect of Exposure to Second-Hand Smoke on the Quality of Life: A Nationwide Population-Based Study from South Korea," PLOS ONE, Public Library of Science, vol. 10(9), pages 1-10, September.

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