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Multisite Evaluation of Point of Care CD4 Testing in Papua New Guinea

Author

Listed:
  • Malin Malagun
  • Gideon Nano
  • Caroline Chevallier
  • Ragagalo Opina
  • Gola Sawiya
  • Joseph Kivavia
  • Albina Kalinoe
  • Kathalina Nathaniel
  • Oscillah Kaminiel
  • John Millan
  • Andrea Carmone
  • Mary Dini
  • Theresa Palou
  • Kum Topma
  • Evelyn Lavu
  • Jessica Markby

Abstract

Laboratory-based CD4 monitoring of HIV patients presents challenges in resource limited settings (RLS) including frequent machine breakdown, poor engineering support and limited cold chain and specimen transport logistics. This study assessed the performance of two CD4 tests designed for use in RLS; the Dynal assay and the Alere PIMA test (PIMA). Accuracy of Dynal and PIMA using venous blood was assessed in a centralised laboratory by comparison to BD FACSCount (BD FACS). Dynal had a mean bias of −50.35 cells/µl (r2 = 0.973, p

Suggested Citation

  • Malin Malagun & Gideon Nano & Caroline Chevallier & Ragagalo Opina & Gola Sawiya & Joseph Kivavia & Albina Kalinoe & Kathalina Nathaniel & Oscillah Kaminiel & John Millan & Andrea Carmone & Mary Dini , 2014. "Multisite Evaluation of Point of Care CD4 Testing in Papua New Guinea," PLOS ONE, Public Library of Science, vol. 9(11), pages 1-15, November.
    • Handle: RePEc:plo:pone00:0112173
    DOI: 10.1371/journal.pone.0112173
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    References listed on IDEAS

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    1. Bruce Larson & Kathryn Schnippel & Buyiswa Ndibongo & Lawrence Long & Matthew P Fox & Sydney Rosen, 2012. "How to Estimate the Cost of Point-of-Care CD4 Testing in Program Settings: An Example Using the Alere Pima™ Analyzer in South Africa," PLOS ONE, Public Library of Science, vol. 7(4), pages 1-8, April.
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