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Cost-Effectiveness of Alternative Strategies for Annual Influenza Vaccination among Children Aged 6 Months to 14 Years in Four Provinces in China

Author

Listed:
  • Lei Zhou
  • Sujian Situ
  • Zijian Feng
  • Charisma Y Atkins
  • Isaac Chun-Hai Fung
  • Zhen Xu
  • Ting Huang
  • Shixiong Hu
  • Xianjun Wang
  • Martin I Meltzer

Abstract

Background: To support policy making, we developed an initial model to assess the cost-effectiveness of potential strategies to increase influenza vaccination rates among children in China. Methods: We studied on children aged 6 months to 14 years in four provinces (Shandong, Henan, Hunan, and Sichuan), with a health care system perspective. We used data from 2005/6 to 2010/11, excluding 2009/10. Costs are reported in 2010 U.S. dollars. Results: In comparison with no vaccination, the mean (range) of Medically Attended Cases averted by the current self-payment policy for the two age groups (6 to 59 months and 60 months to 14 years) was 1,465 (23∼11,132) and 792 (36∼4,247), and the cost effectiveness ratios were $ 0 (-11-51) and $ 37 (6-125) per case adverted, respectively. In comparison with the current policy, the incremental cost effectiveness ratio (ICER) of alternative strategies, OPTION One-reminder and OPTION Two-comprehensive package, decreased as vaccination rate increased. The ICER for children aged 6 to 59 months was lower than that for children aged 60 months to 14 years. Conclusions: The model is a useful tool in identifying elements for evaluating vaccination strategies. However, more data are needed to produce more accurate cost-effectiveness estimates of potential vaccination policies.

Suggested Citation

  • Lei Zhou & Sujian Situ & Zijian Feng & Charisma Y Atkins & Isaac Chun-Hai Fung & Zhen Xu & Ting Huang & Shixiong Hu & Xianjun Wang & Martin I Meltzer, 2014. "Cost-Effectiveness of Alternative Strategies for Annual Influenza Vaccination among Children Aged 6 Months to 14 Years in Four Provinces in China," PLOS ONE, Public Library of Science, vol. 9(1), pages 1-9, January.
    • Handle: RePEc:plo:pone00:0087590
    DOI: 10.1371/journal.pone.0087590
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    Cited by:

    1. Minghuan Jiang & Yilin Gong & Yu Fang & Xuelin Yao & Liuxin Feng & Shan Zhu & Jin Peng & Xinke Shi, 2022. "Parental Preferences of Influenza Vaccination for Children in China: A National Survey with a Discrete Choice Experiment," IJERPH, MDPI, vol. 19(4), pages 1-14, February.

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