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Linkage, Evaluation and Analysis of National Electronic Healthcare Data: Application to Providing Enhanced Blood-Stream Infection Surveillance in Paediatric Intensive Care

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  • Katie Harron
  • Harvey Goldstein
  • Angie Wade
  • Berit Muller-Pebody
  • Roger Parslow
  • Ruth Gilbert

Abstract

Background: Linkage of risk-factor data for blood-stream infection (BSI) in paediatric intensive care (PICU) with bacteraemia surveillance data to monitor risk-adjusted infection rates in PICU is complicated by a lack of unique identifiers and under-ascertainment in the national surveillance system. We linked, evaluated and performed preliminary analyses on these data to provide a practical guide on the steps required to handle linkage of such complex data sources. Methods: Data on PICU admissions in England and Wales for 2003-2010 were extracted from the Paediatric Intensive Care Audit Network. Records of all positive isolates from blood cultures taken for children

Suggested Citation

  • Katie Harron & Harvey Goldstein & Angie Wade & Berit Muller-Pebody & Roger Parslow & Ruth Gilbert, 2013. "Linkage, Evaluation and Analysis of National Electronic Healthcare Data: Application to Providing Enhanced Blood-Stream Infection Surveillance in Paediatric Intensive Care," PLOS ONE, Public Library of Science, vol. 8(12), pages 1-1, December.
    • Handle: RePEc:plo:pone00:0085278
    DOI: 10.1371/journal.pone.0085278
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    Cited by:

    1. Katie Harron, 2022. "A celebration of Harvey Goldstein’s lifetime contributions: A journey in data linkage with Harvey Goldstein," Journal of the Royal Statistical Society Series A, Royal Statistical Society, vol. 185(3), pages 763-767, July.
    2. Katie Harron & Quen Mok & Dyfrig Hughes & Berit Muller-Pebody & Roger Parslow & Padmanabhan Ramnarayan & Ruth Gilbert, 2016. "Generalisability and Cost-Impact of Antibiotic-Impregnated Central Venous Catheters for Reducing Risk of Bloodstream Infection in Paediatric Intensive Care Units in England," PLOS ONE, Public Library of Science, vol. 11(3), pages 1-11, March.

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