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The Clinical Value of Huangqi Injection in the Treatment of Leucopenia: A Meta-Analysis of Clinical Controlled Trials

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  • Changsong Zhang
  • Changtai Zhu
  • Yang Ling
  • Xifa Zhou
  • Chunlei Dong
  • Judong Luo
  • Yongping Liu

Abstract

Background: Huangqi injection is derived from Astragalus membranaceus root. In China, recent reports of Huangqi injection for the treatment of leucopenia have emerged. However, a systematic review of these reports has not been performed. Thus, we conducted a meta-analysis of clinical controlled trials to assess the clinical value of Huangqi injection in the treatment of leucopenia. Methods: We searched the Chinese Biomedical Literature Database (CBM), Wanfang Database, China National Knowledge Infrastructure (CNKI), Chinese Scientific Journals Full-text Database (VIP), as well as PubMed and EMBASE to collect the data about trials of Huangqi injection for treating leucopenia. A meta-analysis was performed using RevMan 5.2 software. Results: A total of 13 studies involving 841 patients were included in this study. The overall study quality was lower according to the Jadad scale. The meta-analysis showed that experimentally treated patients experienced greater therapeutic efficacy and lower white blood cell counts than control groups treated with Western medicine (P

Suggested Citation

  • Changsong Zhang & Changtai Zhu & Yang Ling & Xifa Zhou & Chunlei Dong & Judong Luo & Yongping Liu, 2013. "The Clinical Value of Huangqi Injection in the Treatment of Leucopenia: A Meta-Analysis of Clinical Controlled Trials," PLOS ONE, Public Library of Science, vol. 8(12), pages 1-1, December.
    • Handle: RePEc:plo:pone00:0083123
    DOI: 10.1371/journal.pone.0083123
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    1. Wenbin Zhou & Qiang Ding & Xiuqing Liang & Zhongyuan He & Xiaoming Zha & Xiaoan Liu & Shui Wang, 2012. "The Risk of Amenorrhea Is Related to Chemotherapy-Induced Leucopenia in Breast Cancer Patients Receiving Epirubicin and Taxane Based Chemotherapy," PLOS ONE, Public Library of Science, vol. 7(5), pages 1-5, May.
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