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Bivariate Genome-Wide Association Analysis of the Growth and Intake Components of Feed Efficiency

Author

Listed:
  • Nick V L Serão
  • Dianelys González-Peña
  • Jonathan E Beever
  • Germán A Bollero
  • Bruce R Southey
  • Daniel B Faulkner
  • Sandra L Rodriguez-Zas

Abstract

Single nucleotide polymorphisms (SNPs) associated with average daily gain (ADG) and dry matter intake (DMI), two major components of feed efficiency in cattle, were identified in a genome-wide association study (GWAS). Uni- and multi-SNP models were used to describe feed efficiency in a training data set and the results were confirmed in a validation data set. Results from the univariate and bivariate analyses of ADG and DMI, adjusted by the feedlot beef steer maintenance requirements, were compared. The bivariate uni-SNP analysis identified (P-value

Suggested Citation

  • Nick V L Serão & Dianelys González-Peña & Jonathan E Beever & Germán A Bollero & Bruce R Southey & Daniel B Faulkner & Sandra L Rodriguez-Zas, 2013. "Bivariate Genome-Wide Association Analysis of the Growth and Intake Components of Feed Efficiency," PLOS ONE, Public Library of Science, vol. 8(10), pages 1-11, October.
    • Handle: RePEc:plo:pone00:0078530
    DOI: 10.1371/journal.pone.0078530
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    Cited by:

    1. Aline Camporez Crispim & Matthew John Kelly & Simone Eliza Facioni Guimarães & Fabyano Fonseca e Silva & Marina Rufino Salinas Fortes & Raphael Rocha Wenceslau & Stephen Moore, 2015. "Multi-Trait GWAS and New Candidate Genes Annotation for Growth Curve Parameters in Brahman Cattle," PLOS ONE, Public Library of Science, vol. 10(10), pages 1-19, October.

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