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Use of Liver Stiffness Measurement for Liver Resection Surgery: Correlation with Indocyanine Green Clearance Testing and Post-Operative Outcome

Author

Listed:
  • James Fung
  • Ronnie T P Poon
  • Wan-Ching Yu
  • See-Ching Chan
  • Albert C Y Chan
  • Kenneth S H Chok
  • Tan-To Cheung
  • Wai-Kay Seto
  • Chung-Mau Lo
  • Ching-Lung Lai
  • Man-Fung Yuen

Abstract

Background: Liver stiffness measurement (LSM) using transient elastography has recently become available for the assessment of liver fibrosis. Whether LSM can predict the functional liver reserve in patients undergoing liver resection is not certain. Aim: To correlate liver stiffness measurement (LSM) with indocyanine green (ICG) clearance test and liver biochemistry, and to determine its usefulness in predicting postoperative outcomes in patients undergoing liver resection. Patients and Methods: Transient elastography and ICG clearance test were performed pre-operatively in 44 patients with hepatocellular carcinoma. The LSM and ICG retention rate at 15 minutes (R15) were correlated with pre-operative factors and post-operative outcomes. Results: There was significant correlation between ICG R15 and LSM. In patients with LSM ≥11 kPa vs

Suggested Citation

  • James Fung & Ronnie T P Poon & Wan-Ching Yu & See-Ching Chan & Albert C Y Chan & Kenneth S H Chok & Tan-To Cheung & Wai-Kay Seto & Chung-Mau Lo & Ching-Lung Lai & Man-Fung Yuen, 2013. "Use of Liver Stiffness Measurement for Liver Resection Surgery: Correlation with Indocyanine Green Clearance Testing and Post-Operative Outcome," PLOS ONE, Public Library of Science, vol. 8(8), pages 1-6, August.
    • Handle: RePEc:plo:pone00:0072306
    DOI: 10.1371/journal.pone.0072306
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    Cited by:

    1. Zitong Huang & Jingjing Huang & Tianran Zhou & Hongying Cao & Bo Tan, 2018. "Prognostic value of liver stiffness measurement for the liver-related surgical outcomes of patients under hepatic resection: A meta-analysis," PLOS ONE, Public Library of Science, vol. 13(1), pages 1-15, January.

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