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Diabetes Mellitus and Risk of Bladder Cancer: A Meta-Analysis of Cohort Studies

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  • Zhaowei Zhu
  • Xiaohua Zhang
  • Zhoujun Shen
  • Shan Zhong
  • Xianjin Wang
  • Yingli Lu
  • Chen Xu

Abstract

Background: Increasing evidence suggests that diabetes mellitus (DM) may be associated with an increased risk of bladder cancer. To provide a quantitative assessment of this association, we evaluated the relation between DM and incidence and mortality of bladder cancer in an updated meta-analysis of cohort studies. Results: A total of 29 cohort studies (27 articles) were included in this meta-analysis. DM was associated with an increased incidence of bladder cancer (RR 1.29, 95% CI: 1.08–1.54), with significant evidence of heterogeneity among these studies (p

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  • Zhaowei Zhu & Xiaohua Zhang & Zhoujun Shen & Shan Zhong & Xianjin Wang & Yingli Lu & Chen Xu, 2013. "Diabetes Mellitus and Risk of Bladder Cancer: A Meta-Analysis of Cohort Studies," PLOS ONE, Public Library of Science, vol. 8(2), pages 1-9, February.
    • Handle: RePEc:plo:pone00:0056662
    DOI: 10.1371/journal.pone.0056662
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    Cited by:

    1. Zhaowei Zhu & Jia Zhao & Yinghui Li & Chen Pang & Zhanwei Zhu & Xuepei Zhang, 2019. "Prognostic value of preoperative hydronephrosis in patients with bladder cancer undergoing radical cystectomy: A meta-analysis," PLOS ONE, Public Library of Science, vol. 14(9), pages 1-12, September.

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