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Improved Cardiac MRI Volume Measurements in Patients with Tetralogy of Fallot by Independent End-Systolic and End-Diastolic Phase Selection

Author

Listed:
  • Hendrik G Freling
  • Petronella G Pieper
  • Karin M Vermeulen
  • Jeroen M van Swieten
  • Paul E Sijens
  • Dirk J van Veldhuisen
  • Tineke P Willems

Abstract

Objectives: To investigate to what extent cardiac MRI derived measurements of right ventricular (RV) volumes using the left ventricular (LV) end-systolic and end-diastolic frame misrepresent RV end-systolic and end-diastolic volumes in patients with tetralogy of Fallot (ToF) and a right bundle branch block. Methods: Sixty-five cardiac MRI scans of patients with ToF and a right bundle branch block, and 50 cardiac MRI scans of control subjects were analyzed. RV volumes and function using the end-systolic and end-diastolic frame of the RV were compared to using the end-systolic and end-diastolic frame of the LV. Results: Timing of the RV end-systolic frame was delayed compared to the LV end-systolic frame in 94% of patients with ToF and in 50% of control subjects. RV end-systolic volume using the RV end-systolic instead of LV end-systolic frame was smaller in ToF (median −3.3 ml/m2, interquartile range −1.9 to −5.6 ml/m2; p

Suggested Citation

  • Hendrik G Freling & Petronella G Pieper & Karin M Vermeulen & Jeroen M van Swieten & Paul E Sijens & Dirk J van Veldhuisen & Tineke P Willems, 2013. "Improved Cardiac MRI Volume Measurements in Patients with Tetralogy of Fallot by Independent End-Systolic and End-Diastolic Phase Selection," PLOS ONE, Public Library of Science, vol. 8(1), pages 1-5, January.
    • Handle: RePEc:plo:pone00:0055462
    DOI: 10.1371/journal.pone.0055462
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