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Lesion Length Impacts Long Term Outcomes of Drug-Eluting Stents and Bare Metal Stents Differently

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  • Shang-Hung Chang
  • Chun-Chi Chen
  • Ming-Jer Hsieh
  • Chao-Yung Wang
  • Cheng-Hung Lee
  • I-Chang Hsieh

Abstract

Background: Long lesions have been associated with adverse outcomes in percutaneous coronary interventions with bare metal stents (BMS). However, the exact impact of lesion length on the short- and long-term outcomes of drug-eluting stent (DES) implantations is not as clear. Methods and Results: This study compared the impact of lesion length on angiographic and clinical outcomes of BMS and DES in a single-center prospective registry. Lesion length was divided into tertiles. The primary endpoints were angiographically defined binary in-stent restenosis (ISR) rate and major adverse cardiac event (MACE). Of the 4,312 de novo lesions in 3,447 consecutive patients in the CAPTAIN registry, 2,791 lesions (of 2,246 patients) received BMS, and the remaining 1,521 lesions (of 1,201 patients) received DES. The mean follow-up duration was 4.5 years. The longer the lesion, the higher the ISR rate (14%, 18%, and 29%, p

Suggested Citation

  • Shang-Hung Chang & Chun-Chi Chen & Ming-Jer Hsieh & Chao-Yung Wang & Cheng-Hung Lee & I-Chang Hsieh, 2013. "Lesion Length Impacts Long Term Outcomes of Drug-Eluting Stents and Bare Metal Stents Differently," PLOS ONE, Public Library of Science, vol. 8(1), pages 1-7, January.
    • Handle: RePEc:plo:pone00:0053207
    DOI: 10.1371/journal.pone.0053207
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