IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0048878.html
   My bibliography  Save this article

Gamma-Glutamyltransferase Level and Risk of Hypertension: A Systematic Review and Meta-Analysis

Author

Listed:
  • Cun-Fei Liu
  • Yu-Ting Gu
  • Hai-Ya Wang
  • Ning-Yuan Fang

Abstract

Background: Several prospective observational studies suggest that gamma-glutamyltransferase(GGT) level is positively associated with risk of hypertension. However, these studies draw inconsistent conclusions. Therefore, we conducted a systematic review and meta-analysis to evaluate the exact association between GGT level and subsequent development of hypertension. Methods: We searched Pubmed, Embase, and Science Citation Index (ISI Web of Science) for prospective cohort studies examining the association between GGT level and hypertension. Then, pooled effect estimates (RRs) for the association between GGT level and hypertension were calculated. Results: A total of 13 prospective cohort studies including 43314 participants and 5280 cases of hypertension were included. The pooled RR of hypertension was 1.94(95%CI: 1.55–2.43; P

Suggested Citation

  • Cun-Fei Liu & Yu-Ting Gu & Hai-Ya Wang & Ning-Yuan Fang, 2012. "Gamma-Glutamyltransferase Level and Risk of Hypertension: A Systematic Review and Meta-Analysis," PLOS ONE, Public Library of Science, vol. 7(11), pages 1-7, November.
    • Handle: RePEc:plo:pone00:0048878
    DOI: 10.1371/journal.pone.0048878
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0048878
    Download Restriction: no
    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0048878&type=printable
    Download Restriction: no
    File URL: https://libkey.io/10.1371/journal.pone.0048878?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    Citations

    Citations are extracted by the CitEc Project, subscribe to its RSS feed for this item.
    as


    Cited by:

    1. Pankaj C. Patel & Marcus T. Wolfe, 2021. "Under Pressure: The Effect of Antioxidants on Health Consequences Related to Oxidative Stress," Entrepreneurship Theory and Practice, , vol. 45(1), pages 211-241, January.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0048878. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.