IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0048397.html
   My bibliography  Save this article

Early Hemoperfusion May Improve Survival of Severely Paraquat-Poisoned Patients

Author

Listed:
  • Ching-Wei Hsu
  • Ja-Liang Lin
  • Dan-Tzu Lin-Tan
  • Kuan-Hsing Chen
  • Tzung-Hai Yen
  • Mai-Szu Wu
  • Shih-Chieh Lin

Abstract

Background: Thousands of paraquat (PQ)-poisoned patients continue to die, particularly in developing countries. Although animal studies indicate that hemoperfusion (HP) within 2−4 h after intoxication effectively reduces mortality, the effect of early HP in humans remains unknown. Methods: We analyzed the records of all PQ-poisoned patients admitted to 2 hospitals between 2000 and 2009. Patients were grouped according to early or late HP and high-dose (oral cyclophosphamide [CP] and intravenous dexamethasone [DX]) or repeated pulse (intravenous methylprednisolone [MP] and CP, followed by DX and repeated MP and/or CP) PQ therapy. Early HP was defined as HP

Suggested Citation

  • Ching-Wei Hsu & Ja-Liang Lin & Dan-Tzu Lin-Tan & Kuan-Hsing Chen & Tzung-Hai Yen & Mai-Szu Wu & Shih-Chieh Lin, 2012. "Early Hemoperfusion May Improve Survival of Severely Paraquat-Poisoned Patients," PLOS ONE, Public Library of Science, vol. 7(10), pages 1-9, October.
    • Handle: RePEc:plo:pone00:0048397
    DOI: 10.1371/journal.pone.0048397
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0048397
    Download Restriction: no
    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0048397&type=printable
    Download Restriction: no
    File URL: https://libkey.io/10.1371/journal.pone.0048397?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0048397. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    We have no bibliographic references for this item. You can help adding them by using this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.