IDEAS home Printed from https://ideas.repec.org/a/plo/pone00/0047395.html
   My bibliography  Save this article

Safety of over Twelve Hundred Infant Male Circumcisions Using the Mogen Clamp in Kenya

Author

Listed:
  • Marisa R Young
  • Robert C Bailey
  • Elijah Odoyo-June
  • Tracy E Irwin
  • Walter Obiero
  • Dedan O Ongong'a
  • Jacinta A Badia
  • Kawango Agot
  • Sherry K Nordstrom

Abstract

Background: Several sub-Saharan African countries plan to scale-up infant male circumcision (IMC) for cost-efficient HIV prevention. Little data exist about the safety of IMC in East and southern Africa. We calculated adverse event (AE) rate and risks for AEs associated with introduction of IMC services at five government health facilities in western Kenya. Methods: AE data were analyzed for IMC procedures performed between September, 2009 and November, 2011. Healthy infants aged ≤2 months and weighing ≥2.5 kg were eligible for IMC. Following parental consent, trained clinicians provided IMC services free of charge under local anesthesia using the Mogen clamp. Odds ratios and 95% confidence intervals were used to explore AE risk factors. Findings: A total of 1,239 IMC procedures were performed. Median age of infants was 4 days (IQR = 1, 16). The overall AE rate among infants reviewed post-operatively was 2.7% (18/678; 95%CI: 1.4, 3.9). There was one severe AE involving excision of a small piece of the lateral aspect of the glans penis. Other AEs were mild or moderate and were treated conservatively. Babies one month of age or older were more likely to have an AE (OR 3.20; 95%CI: 1.23, 8.36). AE rate did not differ by nurse versus clinical officer or number of previous procedures performed. Conclusion: IMC services provided in Kenyan Government hospitals in the context of routine IMC programming have AE rates comparable to those in developed countries. The optimal time for IMC is within the first month of life.

Suggested Citation

  • Marisa R Young & Robert C Bailey & Elijah Odoyo-June & Tracy E Irwin & Walter Obiero & Dedan O Ongong'a & Jacinta A Badia & Kawango Agot & Sherry K Nordstrom, 2012. "Safety of over Twelve Hundred Infant Male Circumcisions Using the Mogen Clamp in Kenya," PLOS ONE, Public Library of Science, vol. 7(10), pages 1-5, October.
    • Handle: RePEc:plo:pone00:0047395
    DOI: 10.1371/journal.pone.0047395
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0047395
    Download Restriction: no
    File URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0047395&type=printable
    Download Restriction: no
    File URL: https://libkey.io/10.1371/journal.pone.0047395?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Bertran Auvert & Dirk Taljaard & Emmanuel Lagarde & Joëlle Sobngwi-Tambekou & Rémi Sitta & Adrian Puren, 2005. "Randomized, Controlled Intervention Trial of Male Circumcision for Reduction of HIV Infection Risk: The ANRS 1265 Trial," PLOS Medicine, Public Library of Science, vol. 2(11), pages 1-1, October.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Carl Montague & Nelisiwe Ngcobo & Gethwana Mahlase & Janet Frohlich & Cheryl Pillay & Nonhlanhla Yende-Zuma & Hilton Humphries & Rachael Dellar & Kogieleum Naidoo & Quarraisha Abdool Karim, 2014. "Implementation of Adolescent-Friendly Voluntary Medical Male Circumcision Using a School Based Recruitment Program in Rural KwaZulu-Natal, South Africa," PLOS ONE, Public Library of Science, vol. 9(5), pages 1-7, May.
    2. Nicholas Wilson & Wentao Xiong & Christine Mattson, 2011. "Is Sex Like Driving? Risk Compensation Associated with Male Circumcision in Kisumu, Kenya," Department of Economics Working Papers 2011-14, Department of Economics, Williams College, revised Jan 2012.
    3. Bertran Auvert & Guy Séverin Mahiane & Pascale Lissouba & Thierry Moreau, 2011. "Statistical Power and Estimation of Incidence Rate Ratios Obtained from BED Incidence Testing for Evaluating HIV Interventions among Young People," PLOS ONE, Public Library of Science, vol. 6(8), pages 1-9, August.
    4. Babalwa Zani & Elizabeth D Pienaar & Joy Oliver & Nandi Siegfried, 2011. "Randomized Controlled Trials of HIV/AIDS Prevention and Treatment in Africa: Results from the Cochrane HIV/AIDS Specialized Register," PLOS ONE, Public Library of Science, vol. 6(12), pages 1-9, December.
    5. Paul J Feldblum & Elijah Odoyo-June & Walter Obiero & Robert C Bailey & Stephanie Combes & Catherine Hart & Jaim Jou Lai & Shelly Fischer & Peter Cherutich, 2014. "Safety, Effectiveness and Acceptability of the PrePex Device for Adult Male Circumcision in Kenya," PLOS ONE, Public Library of Science, vol. 9(5), pages 1-8, May.
    6. Kim E Dickson & Nhan T Tran & Julia L Samuelson & Emmanuel Njeuhmeli & Peter Cherutich & Bruce Dick & Tim Farley & Caroline Ryan & Catherine A Hankins, 2011. "Voluntary Medical Male Circumcision: A Framework Analysis of Policy and Program Implementation in Eastern and Southern Africa," PLOS Medicine, Public Library of Science, vol. 8(11), pages 1-13, November.
    7. Jane T Bertrand & Dino Rech & Dickens Omondi Aduda & Sasha Frade & Mores Loolpapit & Michael D Machaku & Mathews Oyango & Webster Mavhu & Alexandra Spyrelis & Linnea Perry & Margaret Farrell & Delivet, 2014. "Systematic Monitoring of Voluntary Medical Male Circumcision Scale-Up: Adoption of Efficiency Elements in Kenya, South Africa, Tanzania, and Zimbabwe," PLOS ONE, Public Library of Science, vol. 9(5), pages 1-10, May.
    8. Elijah Odoyo-June & Kawango Agot & Jonathan M Grund & Frankline Onchiri & Paul Musingila & Edward Mboya & Donath Emusu & Jacob Onyango & Spala Ohaga & Leonard Soo & Boaz Otieno-Nyunya, 2017. "Predictors of voluntary medical male circumcision prevalence among men aged 25-39 years in Nyanza region, Kenya: Results from the baseline survey of the TASCO study," PLOS ONE, Public Library of Science, vol. 12(10), pages 1-10, October.
    9. Sanele Ngcobo & Jacqueline Elizabeth Wolvaardt & Martin Bac & Elize Webb, 2018. "The quality of voluntary medical male circumcision done by mid-level workers in Tshwane District, South Africa: A retrospective analysis," PLOS ONE, Public Library of Science, vol. 13(1), pages 1-7, January.
    10. Nicole A Haberland & Christine A Kelly & Drosin M Mulenga & Barbara S Mensch & Paul C Hewett, 2016. "Women’s Perceptions and Misperceptions of Male Circumcision: A Mixed Methods Study in Zambia," PLOS ONE, Public Library of Science, vol. 11(3), pages 1-15, March.
    11. Webster Mavhu & Karin Hatzold & Susan M Laver & Judith Sherman & Brenda R Tengende & Collin Mangenah & Lisa F Langhaug & Graham Hart & Frances M Cowan, 2012. "Acceptability of Early Infant Male Circumcision as an HIV Prevention Intervention in Zimbabwe: A Qualitative Perspective," PLOS ONE, Public Library of Science, vol. 7(2), pages 1-5, February.
    12. Jonathan Dushoff & Audrey Patocs & Chyun-Fung Shi, 2011. "Modeling the Population-Level Effects of Male Circumcision as an HIV-Preventive Measure: A Gendered Perspective," PLOS ONE, Public Library of Science, vol. 6(12), pages 1-7, December.
    13. Larissa Jennings & Jane Bertrand & Dino Rech & Steven A Harvey & Karin Hatzold & Christopher A Samkange & Dickens S Omondi Aduda & Bennett Fimbo & Peter Cherutich & Linnea Perry & Delivette Castor & E, 2014. "Quality of Voluntary Medical Male Circumcision Services during Scale-Up: A Comparative Process Evaluation in Kenya, South Africa, Tanzania and Zimbabwe," PLOS ONE, Public Library of Science, vol. 9(5), pages 1-9, May.
    14. Gavin George & Michael Strauss & Elias Asfaw, 2017. "The cost of demand creation activities and voluntary medical male circumcision targeting school-going adolescents in KwaZulu-Natal, South Africa," PLOS ONE, Public Library of Science, vol. 12(6), pages 1-14, June.
    15. Amir Sabet Sarvestani & Leonard Bufumbo & James D Geiger & Kathleen H Sienko, 2012. "Traditional Male Circumcision in Uganda: A Qualitative Focus Group Discussion Analysis," PLOS ONE, Public Library of Science, vol. 7(10), pages 1-10, October.
    16. Kathleen E Wirth & Bazghina-werq Semo & Lisa P Spees & Conrad Ntsuape & Scott Barnhart & Jenny H Ledikwe, 2017. "A prospective cohort study of safety and patient satisfaction of voluntary medical male circumcision in Botswana," PLOS ONE, Public Library of Science, vol. 12(11), pages 1-9, November.
    17. Richard T Gray & Andrew Vallely & David P Wilson & John Kaldor & David MacLaren & Angela Kelly-Hanku & Peter Siba & John M Murray & on behalf of the Male Circumcision Acceptability and Impact Study (M, 2014. "Impact of Male Circumcision on the HIV Epidemic in Papua New Guinea: A Country with Extensive Foreskin Cutting Practices," PLOS ONE, Public Library of Science, vol. 9(8), pages 1-9, August.
    18. Limakatso Lebina & Noah Taruberekera & Minja Milovanovic & Karin Hatzold & Miriam Mhazo & Cynthia Nhlapo & Nkeko Tshabangu & Mmatsie Manentsa & Victoria Kazangarare & Millicent Makola & Scott Billy & , 2015. "Piloting PrePex for Adult and Adolescent Male Circumcision in South Africa – Pain Is an Issue," PLOS ONE, Public Library of Science, vol. 10(9), pages 1-12, September.
    19. Thomas A Odeny & Robert C Bailey & Elizabeth A Bukusi & Jane M Simoni & Kenneth A Tapia & Krista Yuhas & King K Holmes & R Scott McClelland, 2012. "Text Messaging to Improve Attendance at Post-Operative Clinic Visits after Adult Male Circumcision for HIV Prevention: A Randomized Controlled Trial," PLOS ONE, Public Library of Science, vol. 7(9), pages 1-7, September.
    20. Dino Rech & Alexandra Spyrelis & Sasha Frade & Linnea Perry & Margaret Farrell & Rebecca Fertziger & Carlos Toledo & Delivette Castor & Emmanuel Njeuhmeli & Dayanund Loykissoonlal & Jane T Bertrand, 2014. "Implications of the Fast-Evolving Scale-Up of Adult Voluntary Medical Male Circumcision for Quality of Services in South Africa," PLOS ONE, Public Library of Science, vol. 9(5), pages 1-10, May.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pone00:0047395. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosone (email available below). General contact details of provider: https://journals.plos.org/plosone/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.