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IVTA as Adjunctive Treatment to PRP and MPC for PDR and Macular Edema: A Meta-Analysis

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  • Lei Liu
  • Xiaomei Wu
  • Jin Geng
  • Zhe Yuan
  • Lei Chen

Abstract

Background: To quantify the effect of a combination treatment of intravitreal triamcinolone acetonide (IVTA) injection, panretinal photocoagulation (PRP), and macular photocoagulation (MPC) in patients with proliferative diabetic retinopathy (PDR) and diabetic macular edema (DME). Methodology/Principal Findings: We conducted a meta-analysis and searched for reports concerning IVTA injection combined with PRP for the treatment of PDR and DME using Medline, EMbase, Web of Science, the Cochrane Library, and Google according to Cochrane evaluation guidelines. The quality of the reports was evaluated using the Jadad score. Only four studies were ultimately included in this meta-analysis and the fixed-effects model was used. Treatment with IVTA injection combined with PRP and MPC significantly improved BCVA (p

Suggested Citation

  • Lei Liu & Xiaomei Wu & Jin Geng & Zhe Yuan & Lei Chen, 2012. "IVTA as Adjunctive Treatment to PRP and MPC for PDR and Macular Edema: A Meta-Analysis," PLOS ONE, Public Library of Science, vol. 7(9), pages 1-9, September.
    • Handle: RePEc:plo:pone00:0044683
    DOI: 10.1371/journal.pone.0044683
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