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Epidemiology of Functional Diarrhea and Comparison with Diarrhea-Predominant Irritable Bowel Syndrome: A Population-Based Survey in China

Author

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  • Yan-Fang Zhao
  • Xiao-Jing Guo
  • Zhan-Sai Zhang
  • Xiu-Qiang Ma
  • Rui Wang
  • Xiao-Yan Yan
  • Jia He

Abstract

Background: The epidemiology of functional diarrhea and its impacts on Chinese remain unclear, and there are no data on the comparative epidemiology of functional diarrhea and diarrhea-predominant irritable bowel syndrome (IBS-D). This study was to explore the epidemiology of functional diarrhea and its impacts, and to identify its distinction from IBS-D. Methods and Findings: A cross-sectional survey was conducted in 16078 respondents, who were interviewed under a randomized stratified multi-stage sampling design in five cities of China. All respondents completed the modified Rome II questionnaire, and the 36-item Short Form health survey (SF-36) was used for assessing health-related quality of life in 20% of the sample. Overall, 248 respondents (1.54%) had functional diarrhea and 277 (1.72%) had IBS-D. Functional diarrhea was positively associated with increasing age and body mass index (trend test P

Suggested Citation

  • Yan-Fang Zhao & Xiao-Jing Guo & Zhan-Sai Zhang & Xiu-Qiang Ma & Rui Wang & Xiao-Yan Yan & Jia He, 2012. "Epidemiology of Functional Diarrhea and Comparison with Diarrhea-Predominant Irritable Bowel Syndrome: A Population-Based Survey in China," PLOS ONE, Public Library of Science, vol. 7(8), pages 1-7, August.
    • Handle: RePEc:plo:pone00:0043749
    DOI: 10.1371/journal.pone.0043749
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