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Epidemiologic and Economic Burden of Influenza in the Outpatient Setting: A Prospective Study in a Subtropical Area of China

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  • Ru-ning Guo
  • Hui-zhen Zheng
  • Li-qun Huang
  • Yong Zhou
  • Xin Zhang
  • Chan-kun Liang
  • Jin-yan Lin
  • Jian-feng He
  • Jin-qing Zhang

Abstract

Objectives: To understand the incidence of outpatient influenza cases in a subtropical area of China and the associated economic burden on patients' families. Methods: A hospital-based prospective study was conducted in Zhuhai City during 2008–2009. All outpatient influenza-like illness (ILI) cases were identified in 28 sentinel hospitals. A representative sample of throat swabs from ILI cases were collected for virus isolation using Madin-Darby canine kidney cells. The incidence of outpatient influenza cases in Zhuhai was estimated on the basis of the number of influenza patients detected by the sentinel sites. A telephone survey on the direct costs associated with illness was conducted as a follow-up. Results: The incidence of influenza was estimated to be 4.1 per 1,000 population in 2008 and 19.2 per 1,000 population in 2009. Children aged

Suggested Citation

  • Ru-ning Guo & Hui-zhen Zheng & Li-qun Huang & Yong Zhou & Xin Zhang & Chan-kun Liang & Jin-yan Lin & Jian-feng He & Jin-qing Zhang, 2012. "Epidemiologic and Economic Burden of Influenza in the Outpatient Setting: A Prospective Study in a Subtropical Area of China," PLOS ONE, Public Library of Science, vol. 7(7), pages 1-7, July.
    • Handle: RePEc:plo:pone00:0041403
    DOI: 10.1371/journal.pone.0041403
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    Cited by:

    1. Xiaozhen Lai & Hongguo Rong & Xiaochen Ma & Zhiyuan Hou & Shunping Li & Rize Jing & Haijun Zhang & Yun Lyu & Jiahao Wang & Huangyufei Feng & Zhibin Peng & Luzhao Feng & Hai Fang, 2021. "The Economic Burden of Influenza-Like Illness among Children, Chronic Disease Patients, and the Elderly in China: A National Cross-Sectional Survey," IJERPH, MDPI, vol. 18(12), pages 1-16, June.
    2. Dan Wang & Tao Zhang & Jing Wu & Yanwei Jiang & Yunfang Ding & Jun Hua & Ying Li & Jun Zhang & Liling Chen & Zijian Feng & Danielle Iuliano & Jeffrey McFarland & Genming Zhao, 2013. "Socio-Economic Burden of Influenza among Children Younger than 5 Years in the Outpatient Setting in Suzhou, China," PLOS ONE, Public Library of Science, vol. 8(8), pages 1-9, August.

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