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Expanding ART for Treatment and Prevention of HIV in South Africa: Estimated Cost and Cost-Effectiveness 2011-2050

Author

Listed:
  • Reuben Granich
  • James G Kahn
  • Rod Bennett
  • Charles B Holmes
  • Navneet Garg
  • Celicia Serenata
  • Miriam Lewis Sabin
  • Carla Makhlouf-Obermeyer
  • Christina De Filippo Mack
  • Phoebe Williams
  • Louisa Jones
  • Caoimhe Smyth
  • Kerry A Kutch
  • Lo Ying-Ru
  • Marco Vitoria
  • Yves Souteyrand
  • Siobhan Crowley
  • Eline L Korenromp
  • Brian G Williams

Abstract

Background: Antiretroviral Treatment (ART) significantly reduces HIV transmission. We conducted a cost-effectiveness analysis of the impact of expanded ART in South Africa. Methods: We model a best case scenario of 90% annual HIV testing coverage in adults 15–49 years old and four ART eligibility scenarios: CD4 count

Suggested Citation

  • Reuben Granich & James G Kahn & Rod Bennett & Charles B Holmes & Navneet Garg & Celicia Serenata & Miriam Lewis Sabin & Carla Makhlouf-Obermeyer & Christina De Filippo Mack & Phoebe Williams & Louisa , 2012. "Expanding ART for Treatment and Prevention of HIV in South Africa: Estimated Cost and Cost-Effectiveness 2011-2050," PLOS ONE, Public Library of Science, vol. 7(2), pages 1-15, February.
    • Handle: RePEc:plo:pone00:0030216
    DOI: 10.1371/journal.pone.0030216
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    References listed on IDEAS

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    1. Rochelle P Walensky & Robin Wood & Andrea L Ciaranello & A David Paltiel & Sarah B Lorenzana & Xavier Anglaret & Adam W Stoler & Kenneth A Freedberg & for the CEPAC-International Investigators, 2010. "Scaling Up the 2010 World Health Organization HIV Treatment Guidelines in Resource-Limited Settings: A Model-Based Analysis," PLOS Medicine, Public Library of Science, vol. 7(12), pages 1-12, December.
    2. Stephen Resch & Eline Korenromp & John Stover & Matthew Blakley & Carleigh Krubiner & Kira Thorien & Robert Hecht & Rifat Atun, 2011. "Economic Returns to Investment in AIDS Treatment in Low and Middle Income Countries," PLOS ONE, Public Library of Science, vol. 6(10), pages 1-9, October.
    3. S.J. Goldie & Y. Yazdanpanah & E. Losina & M.C. Weinstein & X. Anglaret & R.P. Walensky & H.E. Hsu & A. Kimmel & C. Holmes & J.E. Kaplan & K.A. Freedberg, 2006. "Cost-effectiveness of HIV treatment in Resource-Poor Settings - The case of Côte d'Ivoire," Post-Print hal-00199992, HAL.
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