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Health Related Quality of Life among Patients with Tuberculosis and HIV in Thailand

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Listed:
  • Wanitchaya Kittikraisak
  • Pritaporn Kingkaew
  • Yot Teerawattananon
  • Jomkwan Yothasamut
  • Supalert Natesuwan
  • Weerawat Manosuthi
  • Virasakdi Chongsuvivatwong
  • Sara J Whitehead

Abstract

Introduction: Health utilities of tuberculosis (TB) patients may be diminished by side effects from medication, prolonged treatment duration, physical effects of the disease itself, and social stigma attached to the disease. Methods: We collected health utility data from Thai patients who were on TB treatment or had been successfully treated for TB for the purpose of economic modeling. Structured questionnaire and EuroQol (EQ-5D) and EuroQol visual analog scale (EQ-VAS) instruments were used as data collection tools. We compared utility of patients with two co-morbidities calculated using multiplicative model (UCAL) with the direct measures and fitted Tobit regression models to examine factors predictive of health utility and to assess difference in health utilities of patients in various medical conditions. Results: Of 222 patients analyzed, 138 (62%) were male; median age at enrollment was 40 years (interquartile range [IQR], 35–47). Median monthly household income was 6,000 Baht (187 US$; IQR, 4,000–15,000 Baht [125–469 US$]). Concordance correlation coefficient between utilities measured using EQ-5D and EQ-VAS (UEQ-5D and UVAS, respectively) was 0.6. UCAL for HIV-infected TB patients was statistically different from the measured UEQ-5D (p-value

Suggested Citation

  • Wanitchaya Kittikraisak & Pritaporn Kingkaew & Yot Teerawattananon & Jomkwan Yothasamut & Supalert Natesuwan & Weerawat Manosuthi & Virasakdi Chongsuvivatwong & Sara J Whitehead, 2012. "Health Related Quality of Life among Patients with Tuberculosis and HIV in Thailand," PLOS ONE, Public Library of Science, vol. 7(1), pages 1-8, January.
    • Handle: RePEc:plo:pone00:0029775
    DOI: 10.1371/journal.pone.0029775
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    References listed on IDEAS

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    1. Thaddeus L Miller & Scott J N McNabb & Peter Hilsenrath & Jotam Pasipanodya & Stephen E Weis, 2009. "Personal and Societal Health Quality Lost to Tuberculosis," PLOS ONE, Public Library of Science, vol. 4(4), pages 1-7, April.
    2. Marie-Josée Dion & Pierre Tousignant & Jean Bourbeau & Dick Menzies & Kevin Schwartzman, 2002. "Measurement of Health Preferences among Patients with Tuberculous Infection and Disease," Medical Decision Making, , vol. 22(1_suppl), pages 102-114, September.
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