IDEAS home Printed from https://ideas.repec.org/a/plo/pntd00/0006043.html
   My bibliography  Save this article

Systematic review of community-based, school-based, and combined delivery modes for reaching school-aged children in mass drug administration programs for schistosomiasis

Author

Listed:
  • Michael Burnim
  • Julianne A Ivy
  • Charles H King

Abstract

Background: The mainstay of current schistosomiasis control programs is mass preventive chemotherapy of school-aged children with praziquantel. This treatment is delivered through school-based, community-based, or combined school- and community-based systems. Attaining very high coverage rates for children is essential in mass schistosomiasis treatment programs, as is ensuring that there are no persistently untreated subpopulations, a potential challenge for school-based programs in areas with low school enrollment. This review sought to compare the different treatment delivery methods based both on their coverage of school-aged children overall and on their coverage specifically of non-enrolled children. In addition, qualitative community or programmatic factors associated with high or low coverage rates were identified, with suggestions for overall coverage improvement. Methodology/Principal findings: This review was registered prospectively with PROSPERO (CRD 42015017656). Five hundred forty-nine publication of potential relevance were identified through database searches, reference lists, and personal communications. Eligible studies included those published before October 2015, written in English or French, containing quantitative or qualitative data about coverage rates for MDA of school-aged children with praziquantel. Among the 22 selected studies, combined community- and school-based programs achieved the highest median coverage rates (89%), followed by community-based programs (72%). School-based programs had both the lowest median coverage of children overall (49%) and the lowest coverage of the non-enrolled subpopulation of children. Qualitatively, major factors affecting program success included fear of side effects, inadequate education about schistosomiasis, lack of incentives for drug distributors, and inequitable distribution to minority groups. Conclusions/Significance: This review provides an evidence-based framework for the development of future schistosomiasis control programs. Based on our results, a combined community and school-based delivery system should maximize coverage for both in- and out-of-school children, especially when combined with interventions such as snacks for treated children, educational campaigns, incentives for drug distributors, and active inclusion of marginalized groups. Trial registration: ClinicalTrials.gov CRD42015017656 Author summary: Schistosomiasis is a chronic inflammatory condition, caused by parasitic flukes, that affects over 290 million people worldwide. Consequences of infection include anemia, stunted growth, liver abnormalities, and subfertility. Currently, the main approach to schistosomiasis control involves mass preventive treatment of school-aged children in endemic areas. The treatment, praziquantel, can be distributed through school-based, community-based, or combined school- and community-based systems. The first part of this systematic review compared the three delivery modes and found that combined delivery resulted in the best overall coverage of school-aged children, with community-only delivery the next-best approach. School-only delivery not only had the lowest overall coverage, but especially fell behind in targeting children not enrolled in school. As a whole, these results support the more frequent use of a combined approach to delivery in order to achieve the highest coverage rates and ensure that out-of-school children are not left persistently untreated. In the second part of this review the qualitative factors affecting program success were examined. The results indicate that overall treatment coverage can be improved via small interventions, such as snacks for participating children to reduce drug side effects, educational campaigns about schistosomiasis, incentives for drug distributors, and active inclusion of marginalized groups.

Suggested Citation

  • Michael Burnim & Julianne A Ivy & Charles H King, 2017. "Systematic review of community-based, school-based, and combined delivery modes for reaching school-aged children in mass drug administration programs for schistosomiasis," PLOS Neglected Tropical Diseases, Public Library of Science, vol. 11(10), pages 1-16, October.
  • Handle: RePEc:plo:pntd00:0006043
    DOI: 10.1371/journal.pntd.0006043
    as

    Download full text from publisher

    File URL: https://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0006043
    Download Restriction: no

    File URL: https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0006043&type=printable
    Download Restriction: no

    File URL: https://libkey.io/10.1371/journal.pntd.0006043?utm_source=ideas
    LibKey link: if access is restricted and if your library uses this service, LibKey will redirect you to where you can use your library subscription to access this item
    ---><---

    References listed on IDEAS

    as
    1. Jacqueline Leslie & Amadou Garba & Elisa Bosque Oliva & Arouna Barkire & Amadou Aboubacar Tinni & Ali Djibo & Idrissa Mounkaila & Alan Fenwick, 2011. "Schistosomiais and Soil-Transmitted Helminth Control in Niger: Cost Effectiveness of School Based and Community Distributed Mass Drug Administration," PLOS Neglected Tropical Diseases, Public Library of Science, vol. 5(10), pages 1-11, October.
    2. Alison Krentel & Peter U Fischer & Gary J Weil, 2013. "A Review of Factors That Influence Individual Compliance with Mass Drug Administration for Elimination of Lymphatic Filariasis," PLOS Neglected Tropical Diseases, Public Library of Science, vol. 7(11), pages 1-12, November.
    3. Jack E T Grimes & David Croll & Wendy E Harrison & Jürg Utzinger & Matthew C Freeman & Michael R Templeton, 2014. "The Relationship between Water, Sanitation and Schistosomiasis: A Systematic Review and Meta-analysis," PLOS Neglected Tropical Diseases, Public Library of Science, vol. 8(12), pages 1-12, December.
    Full references (including those not matched with items on IDEAS)

    Most related items

    These are the items that most often cite the same works as this one and are cited by the same works as this one.
    1. Sarah C L Knowles & Hugh J W Sturrock & Hugo Turner & Jane M Whitton & Charlotte M Gower & Samuel Jemu & Anna E Phillips & Aboulaye Meite & Brent Thomas & Karsor Kollie & Catherine Thomas & Maria P Re, 2017. "Optimising cluster survey design for planning schistosomiasis preventive chemotherapy," PLOS Neglected Tropical Diseases, Public Library of Science, vol. 11(5), pages 1-21, May.
    2. Alison Krentel & Rita Damayanti & Christiana Rialine Titaley & Nugroho Suharno & Mark Bradley & Timothy Lynam, 2016. "Improving Coverage and Compliance in Mass Drug Administration for the Elimination of LF in Two ‘Endgame’ Districts in Indonesia Using Micronarrative Surveys," PLOS Neglected Tropical Diseases, Public Library of Science, vol. 10(11), pages 1-22, November.
    3. Andréa Gazzinelli & Roberta Oliveira-Prado & Leonardo Ferreira Matoso & Bráulio M Veloso & Gisele Andrade & Helmut Kloos & Jeffrey M Bethony & Renato M Assunção & Rodrigo Correa-Oliveira, 2017. "Schistosoma mansoni reinfection: Analysis of risk factors by classification and regression tree (CART) modeling," PLOS ONE, Public Library of Science, vol. 12(8), pages 1-16, August.
    4. Behera, Bhagirath & Rahut, Dil Bahadur & Sethi, Narayan, 2020. "Analysis of household access to drinking water, sanitation, and waste disposal services in urban areas of Nepal," Utilities Policy, Elsevier, vol. 62(C).
    5. Keating, Emily & Tadesse, Gemechu & Dejene, Nigussie Geletu & Yard, Elodie & Appleby, Laura Jane & Cardwell, Jacqueline M, 2019. "Local Perceptions of an Integrated School Health and Nutrition Programme involving WASH, school feeding and deworming in Southwest Ethiopia," SocArXiv s9ac7_v1, Center for Open Science.
    6. Uffe Christian Braae & Brecht Devleesschauwer & Sarah Gabriël & Pierre Dorny & Niko Speybroeck & Pascal Magnussen & Paul Torgerson & Maria Vang Johansen, 2016. "CystiSim – An Agent-Based Model for Taenia solium Transmission and Control," PLOS Neglected Tropical Diseases, Public Library of Science, vol. 10(12), pages 1-17, December.
    7. Meginnis, Keila & Hanley, Nick & Mujumbusi, Lazaaro & Lamberton, Poppy H.L., 2020. "Non-monetary numeraires: Varying the payment vehicle in a choice experiment for health interventions in Uganda," Ecological Economics, Elsevier, vol. 170(C).
    8. A Maphumulo & O Mahomed & B Vennervald & S G Gundersen & M Taylor & E F Kjetland, 2020. "The cost of a school based mass treatment of schistosomiasis in Ugu District, KwaZulu Natal, South Africa in 2012," PLOS ONE, Public Library of Science, vol. 15(6), pages 1-13, June.
    9. Sclar, G.D. & Penakalapati, G. & Caruso, B.A. & Rehfuess, E.A. & Garn, J.V. & Alexander, K.T. & Freeman, M.C. & Boisson, S. & Medlicott, K. & Clasen, T., 2018. "Exploring the relationship between sanitation and mental and social well-being: A systematic review and qualitative synthesis," Social Science & Medicine, Elsevier, vol. 217(C), pages 121-134.

    More about this item

    Statistics

    Access and download statistics

    Corrections

    All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this item's handle: RePEc:plo:pntd00:0006043. See general information about how to correct material in RePEc.

    If you have authored this item and are not yet registered with RePEc, we encourage you to do it here. This allows to link your profile to this item. It also allows you to accept potential citations to this item that we are uncertain about.

    If CitEc recognized a bibliographic reference but did not link an item in RePEc to it, you can help with this form .

    If you know of missing items citing this one, you can help us creating those links by adding the relevant references in the same way as above, for each refering item. If you are a registered author of this item, you may also want to check the "citations" tab in your RePEc Author Service profile, as there may be some citations waiting for confirmation.

    For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: plosntds (email available below). General contact details of provider: https://journals.plos.org/plosntds/ .

    Please note that corrections may take a couple of weeks to filter through the various RePEc services.

    IDEAS is a RePEc service. RePEc uses bibliographic data supplied by the respective publishers.